Wszystkie zdjęcia(1)
Kluczowe dokumenty
I9276
Interleukin-10 human
≥97% (SDS-PAGE), recombinant, expressed in baculovirus infected Sf21 cells, lyophilized powder, suitable for cell culture
Synonim(y):
IL-10
Zaloguj sięWyświetlanie cen organizacyjnych i kontraktowych
About This Item
Polecane produkty
pochodzenie biologiczne
human
Poziom jakości
rekombinowane
expressed in baculovirus infected Sf21 cells
Próba
≥97% (SDS-PAGE)
Formularz
lyophilized powder
siła działania
0.1-0.5 ng/mL EC50
masa cząsteczkowa
18 kDa
opakowanie
pkg of 5 μg
metody
cell culture | mammalian: suitable
zanieczyszczenia
endotoxin, tested
numer dostępu UniProt
temp. przechowywania
−20°C
informacje o genach
human ... IL10(3586)
Szukasz podobnych produktów? Odwiedź Przewodnik dotyczący porównywania produktów
Zastosowanie
Interleukina-10 (IL-10) u ludzi została wykorzystana do badania wpływu IL-10 na obrót proteoglikanu chrząstki. Została ona wykorzystana jako antygen do analizy wzorców reaktywności autoprzeciwciał u zdrowych ludzi i osób cierpiących na cukrzycę typu 1.
Działania biochem./fizjol.
IL-10 is an important regulator of the functions of lymphoid and myeloid cells. IL-10 can block the activation of cytokine synthesis and several accessory functions of macrophages. Human and mouse IL-10 share a 73% sequence homology. However, human IL-10 acts on both human and mouse target cells, while mouse IL-10 has species-specific activity. In mouse, the cellular sources of IL-10 consist of Th2 cells, activated fetal thymocytes, macrophages, keratinocytes, LY-1+ (CD5+), and normal B cells. In human, the cellular sources of IL-10 consist of CD4+ T cells and T cell clones, thymocytes, B cells, B cell lymphomas, macrophages, mast cell lines and keratinocytes. IL-10 stimulates the growth of stem cells, mast cells and thymocytes. IL-10 enhances cytotoxic T cell development, and co-stimulates B cell differentiation and Ig secretion. IL-10 regulates angiogenesis by inducing the cell-type dependent expression of either angiogenic or angiostatic factors.
Interleukin-10 regulates lymphoid and myeloid cell functions. It blocks the activation of cytokine synthesis and several accessory functions of macrophages. IL-10 enhances cytotoxic T cell development and co-stimulates B cell differentiation and Ig secretion. IL-10 regulates angiogenesis by inducing cell-type dependent expression of either angiogenic or angiostatic factors.
Regulates lymphoid and myeloid cell functions; blocks the activation of cytokine synthesis and several accessory functions of macrophages; enhances cytotoxic T cell development and co-stimulates B cell differentiation and Ig secretion.
Postać fizyczna
Lyophilized from a 0.2 μm filtered solution of phosphate buffered saline, pH 7.4, containing 50 μg bovine serum albumin/μg IL-10
Ta strona może zawierać tekst przetłumaczony maszynowo.
Kod klasy składowania
11 - Combustible Solids
Klasa zagrożenia wodnego (WGK)
WGK 3
Temperatura zapłonu (°F)
Not applicable
Temperatura zapłonu (°C)
Not applicable
Środki ochrony indywidualnej
Eyeshields, Gloves, type N95 (US)
Wybierz jedną z najnowszych wersji:
Masz już ten produkt?
Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.
Klienci oglądali również te produkty
Digitoxin metabolism by rat liver microsomes.
A Schmoldt et al.
Biochemical pharmacology, 24(17), 1639-1641 (1975-09-01)
Francisco J Quintana et al.
Journal of autoimmunity, 21(1), 65-75 (2003-08-02)
Informatic methodologies are being applied successfully to analyze the complexity of the genome. But beyond the genome, the immune system reflects the state of the body in health and disease. Traditionally, immunologists have reduced the immune system, where possible, to
Hiroko Tsuji et al.
Circulation research, 106(10), 1613-1623 (2010-05-29)
Amniotic membrane is known to have the ability to transdifferentiate into multiple organs and is expected to stimulate a reduced immunologic reaction. Determine whether human amniotic membrane-derived mesenchymal cells (hAMCs) can be an ideal allograftable stem cell source for cardiac
Martina Severa et al.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research, 35(9), 668-681 (2015-04-30)
Plasmacytoid dendritic cells (pDCs) display altered immune-phenotype in multiple sclerosis (MS) patients and are found actively recruited in postmortem MS brain lesions, implying that their immune regulation may represent an important aspect of MS pathogenesis. Because of the reported Toll-like
Adriana Weinberg et al.
PloS one, 10(4), e0122431-e0122431 (2015-04-16)
Influenza infections have high frequency and morbidity in HIV-infected pregnant women, underscoring the importance of vaccine-conferred protection. To identify the factors that determine vaccine immunogenicity in this group, we characterized the relationship of B- and T-cell responses to pandemic H1N1
Nasz zespół naukowców ma doświadczenie we wszystkich obszarach badań, w tym w naukach przyrodniczych, materiałoznawstwie, syntezie chemicznej, chromatografii, analityce i wielu innych dziedzinach.
Skontaktuj się z zespołem ds. pomocy technicznej