I7908

IL-2 human

≥98% (SDS-PAGE and HPLC), recombinant, expressed in Pichia pastoris, lyophiilized powder, suitable for cell culture

• Synonim(y): IL-2, Interleukin-2, T-cell growth factor
• Numer MDL: MFCD00165721
• Kod UNSPSC: 12352202
• NACRES: NA.75

Właściwości

• Nazwa produktu: Interleukin-2 human, recombinant, expressed in Pichia pastoris, suitable for cell culture
• pochodzenie biologiczne: human
• Poziom jakości: 200
• rekombinowane: expressed in Pichia pastoris
• Próba: ≥98% (SDS-PAGE and HPLC)
• Formularz: lyophilized powder
• masa cząsteczkowa: predicted mol wt ~15 kDa
• opakowanie: pkg of 10KU
• metody: cell culture | mammalian: suitable
• zanieczyszczenia: endotoxin, tested
• numer dostępu UniProt: P60568
• Warunki transportu: dry ice
• temp. przechowywania: −20°C
• informacje o genach: human ... IL2(3558)

Opis

Zastosowanie

Interleukin-2 human has been used to assess changes in tumor necrosis factor receptor 1 (TNFR1). It has also been used in TNFR2 expression on Tregs.

Działania biochem./fizjol.

Interleukin 2 (IL2) is a pro-inflammatory cytokine. It consists of three subunits, in which the β subunit is important for receptor mediated signaling. IL2 enhances the development of T regulatory cells and plays a crucial role in antitumor immunity.

Interleukin-2 (IL-2) is an immunomodulatory factor produced by certain subsets of T lymphocytes. This lympho­kine promotes long term growth of acti­vated T cells and related cell types. IL-2 plays a role in the activation and proliferation of NK cells, induces γ-inter­feron and B cell growth factor secretion, and modulates the expression of the IL-2 receptor.

Postać fizyczna

Lyophilized from a 0.2 μm filtered solution in 50 mM sodium phosphate buffer, pH 7.0, containing 0.1% human serum albumin per 0.1 mL of cytokine.

Komentarz do analizy

The biological activity is tested in a cell proliferation assay using an IL-2 dependent murine cytotoxic T cell line, CTLL-2.

Ta strona może zawierać tekst przetłumaczony maszynowo.

Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 13 - Non Combustible Solids
• Klasa zagrożenia wodnego (WGK): WGK 3
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable
• Środki ochrony indywidualnej: Eyeshields, Gloves, type N95 (US)