I1774
Iturin A from Bacillus subtilis
≥95% (HPLC), suitable for microbiological culture
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About This Item
Polecane produkty
Nazwa produktu
Iturin A from Bacillus subtilis, ≥95% (HPLC)
pochodzenie biologiczne
Bacillus subtilis
Poziom jakości
Próba
≥95% (HPLC)
Formularz
powder
metody
microbiological culture: suitable
kolor
white to yellow
rozpuszczalność
ethanol: soluble 9.80-10.20 mg/mL
spektrum działania antybiotyku
fungi
Tryb działania
cell membrane | interferes
temp. przechowywania
2-8°C
Zastosowanie
Iturin A was used in the study of Bacillomycin D (an iturin with antifungal activity against Aspergillus flavus).
Działania biochem./fizjol.
IturinA exhibits strong antifungal activity against pathogenic yeast and fungi. It interacts with the cytoplasmic membrane of the target cell forming ion conducting pores. Its mode of action could be attributed to its interaction with sterols and phospholipids. The compound causes the release of exo-vesicles from human erythrocytes.
Inne uwagi
A family of lipopeptides characterized by a heptapeptide cyclized with a C13-C17 β-amino fatty acid. Composed mainly of C14-C15 β-amino acids.
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Kod klasy składowania
11 - Combustible Solids
Klasa zagrożenia wodnego (WGK)
WGK 3
Temperatura zapłonu (°F)
Not applicable
Temperatura zapłonu (°C)
Not applicable
Środki ochrony indywidualnej
Eyeshields, Gloves, type N95 (US)
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Shinji Mizumoto et al.
Applied microbiology and biotechnology, 76(1), 101-108 (2007-05-04)
Iturin A, a lipopeptide antibiotic produced by Bacillus subtilis RB14-CS, suppresses the growth of various plant pathogens. Here, enhancement of iturin A production in solid-state fermentation (SSF) on okara, a soybean curd residue produced during tofu manufacturing, was accomplished using
Jochen Blom et al.
Journal of bacteriology, 194(7), 1845-1846 (2012-03-13)
The genome of the rhizobacterium Bacillus amyloliquefaciens subsp. plantarum CAU B946 was 4.02 Mb in size and harbored 3,823 genes (coding sequences [CDS]). Nine giant gene clusters were dedicated to nonribosomal synthesis of antimicrobial compounds. Remarkably, strain CAU B946 possessed
Dehui Yao et al.
World journal of microbiology & biotechnology, 28(3), 985-991 (2012-07-19)
The strain 3-10 was isolated from soil and identified as B. subtilis according to morphological and physiological characteristics and nucleotide sequence of 16S rRNA. It co-produced anti-fungal iturin A and fertilizer synergist of poly-γ-glutamic acid (γ-PGA) under solid state fermentation
Minakshi Grover et al.
Current microbiology, 60(2), 99-106 (2009-09-25)
Bacillus subtilis strain RP24, isolated from rhizoplane of field grown pigeon pea, exhibited in vitro antagonism against a wide range of phytopathogenic fungi. An attempt was made to partially purify and characterize the diffusible antifungal metabolite/s produced by the strain
Jun Yuan et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 879(26), 2746-2750 (2011-08-30)
Iturin A, a powerful antifungal surfactant, is a kind of bacterial lipopeptide produced by Bacillus strains. This study addresses the use of an aqueous two-phase system (ATPS) using ethanol/ammonium sulfate to extract iturin A from Bacillus amyloliquefaciens NJN-6 fermentation broth
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