I1521

DES (1-6) IGF II

lyophilized powder, recombinant, expressed in E. coli, suitable for cell culture

• Numer CAS: 141909-47-9
• Numer MDL: MFCD00285687
• Kod UNSPSC: 12352202
• NACRES: NA.77

Właściwości

• pochodzenie biologiczne: human
• rekombinowane: expressed in E. coli
• Próba: ≥95% (HPLC)
• Postać: lyophilized powder
• siła działania: ≤100 ng/mL ED₅₀
• masa cząsteczkowa: 6,765 Da
• opakowanie: pkg of 20 μg
• warunki przechowywania: avoid repeated freeze/thaw cycles
• metody: cell culture | mammalian: suitable
• zanieczyszczenia: endotoxin, tested
• kolor: white
• numer dostępu UniProt: P01344
• temp. przechowywania: 2-8°C
• informacje o genach: human ... IGF2(3481)

Opis

Opis ogólny

DES (1-6) IGF-II is a 61 amino acid analog of human insulin-like growth factor II, lacking the first six N-terminal amimo acids. DES (1-6) IGF-II exhibits reduced affinity for IGF binding proteins (IGFBPs), which are known to inhibit the actions of IGF′s.

Zastosowanie

Used for studies of IGF-II function in cell culture applications. Use in combination with IGF-I, insulin and other forms of IGF-II to study receptor functions and cell signaling.

Inne uwagi

Recombinant analog of insulin-like growth factor II.

Uwaga dotycząca przygotowania

Prepared from 0.1 M acetic acid.

Synthesized recombinantly in E. coli using a patented fusion protein expression system, DES (1-6) IGF-II is then purified by liquid chromatography. DES (1-6) IGF-II has been developed as an inexpensive, high quality potent analog of IGF-II for use as a growth factor supplement in cell culture. DES (1-6) IGF-II is supplied as a powder, lyophilized from 0.1 M acetic acid. Molecular weight is 6,765 daltons.

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