FLAAS

Adenosine 5′-triphosphate (ATP) disodium salt hydrate

vial of ~1 mg ATP

• Synonim(y): ATP disodium hydrate
• Wzór liniowy: C₁₀H₁₄N₅O₁₃P₃Na₂ · xH₂O
• Numer CAS: 34369-07-8
• Masa cząsteczkowa: 551.14 (anhydrous basis)
• Numer WE: 213-579-1
• Numer MDL: MFCD00150755
• Kod UNSPSC: 12352202
• eCl@ss: 32160414
• Identyfikator substancji w PubChem: 24895005
• NACRES: NA.26

Właściwości

• pochodzenie biologiczne: bacterial (Corynebacterium sp)
• Poziom jakości: 200
• Próba: ≥90%
• Postać: lyophilized powder
• opakowanie: vial of ~1 mg ATP
• temp. przechowywania: −20°C
• ciąg SMILES: Nc1ncnc2n(cnc12)[C@@H]3O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]3O
• InChI: 1S/C10H16N5O13P3.2Na.H2O/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(26-10)1-25-30(21,22)28-31(23,24)27-29(18,19)20;;;/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H,23,24)(H2,11,12,13)(H2,18,19,20);;;1H2/q;2*+1;/p-2/t4-,6-,7-,10-;;;/m1.../s1
• Klucz InChI: NTBQNWBHIXNPRU-MSQVLRTGSA-L

Opis

Zastosowanie

Adenosine 5′-triphosphate (ATP) disodium salt hydrate has been:

• used as a standard to measure ATP by bioluminescence method
• used in kinase buffer to assess the interaction between death-associated protein kinases (DAPK2) and 14-3-3-β
• used as a standard in ATP colorimetric assay

Działania biochem./fizjol.

Adenosine 5′-triphosphate (ATP) is one of the nucleoside triphosphate present in living system. It controls various biologic processes such as glucose metabolism, muscle contraction and neurotransmission. Apart from this, ATP serves as an important energy source for the cell. Administration of ATP might be useful in the treatment of non-small-cell lung cancer.

Adenosine 5′-triphosphate was shown to have inhibitory effects on the inflammatory response by abrogating secretion of TNF-α and promoting secretion of Interleukin-10.

P₂ purinergic agonist; increases activity of Ca²⁺-activated K⁺ channels; substrate for ATP-dependent enzyme systems

Ilość

Each vial contains ~1.2 mg of Na₂ATP • 3H₂O equivalent to ~1.0 mg of ATP (2.0 μmol). Actual amount printed on the label.

Uwaga dotycząca przygotowania

Prepared to be substantially vanadium-free.

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Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 11 - Combustible Solids
• Klasa zagrożenia wodnego (WGK): WGK 2
• Środki ochrony indywidualnej: Eyeshields, Gloves, type N95 (US)