A6559

Adenosine 5′-triphosphate disodium salt solution

Crystalline ATP, HPLC purified, aqueous solution for RNA transcription

• Synonim(y): ATP
• Numer CAS: 987-65-5
• Numer MDL: MFCD00080339
• Kod UNSPSC: 41106305
• eCl@ss: 32160414
• Identyfikator substancji w PubChem: 24891106
• NACRES: NA.52

Właściwości

• Poziom jakości: 300
• Postać: liquid
• stężenie: 100 mM in H₂O (adjusted to pH 7 with Trizma^®; base)
• obecność zanieczyszczeń: DNase, RNase, none detected
• Warunki transportu: dry ice
• temp. przechowywania: −20°C
• ciąg SMILES: [Na+].[Na+].Nc1ncnc2n(cnc12)[C@@H]3O[C@H](COP(O)(=O)OP([O-])(=O)OP(O)([O-])=O)[C@@H](O)[C@H]3O
• InChI: 1S/C10H16N5O13P3.2Na/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(26-10)1-25-30(21,22)28-31(23,24)27-29(18,19)20;;/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H,23,24)(H2,11,12,13)(H2,18,19,20);;/q;2*+1/p-2/t4-,6-,7-,10-;;/m1../s1
• Klucz InChI: TTWYZDPBDWHJOR-IDIVVRGQSA-L

Opis

Opis ogólny

Adenosine 5′-triphosphate disodium salt solution is suitable for use in molecular biology applications such as kinase reactions or DNA-dependent RNA polymerase transcription.

Zastosowanie

Adenosine 5′-triphosphate disodium salt solution has been used:

• as a standard to evaluate the extracellular ATP release from marginal cells of stria vascular
• as a component of the internal pipette solution to establish a recording electrode to study neurite stretching
• in in vitro VPS34 (catalytic subunit of the phosphatidylinositol 3-kinase (PtdIns3K) complex) activity assay
• as a component of lysis and resealing buffers for ATP studies
• in spectrophotometric measurement of H⁺ transport in fluorescein isothiocyanate (FITC)-dextran loaded A549 (adenocarcinomic human alveolar basal epithelial cells) and HeLa cells
• to induce pyroptosis in lipopolysaccharide treated fibroblast-like synoviocytes (FLSs)

Działania biochem./fizjol.

Adenosine 5′-triphosphate (ATP) is an important energy currency in all living organisms. It possesses high phosphate transfer potential. ATP is involved in several biological processes such as membrane transport, muscle contraction and synthesis, and degradation of biological molecules. It plays a role as an intracellular and extracellular signaling molecule in certain cellular processes such as cell motility, organ development, neurotransmission, and insulin secretion.

Informacje prawne

Trizma is a registered trademark of Merck KGaA, Darmstadt, Germany

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Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 10 - Combustible liquids
• Klasa zagrożenia wodnego (WGK): WGK 1
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable
• Środki ochrony indywidualnej: Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)