U1006

Uridine 5′-triphosphate trisodium salt solution

HPLC purified, aqueous solution for RNA polymerase transcription

• Synonim(y): UTP
• Numer MDL: MFCD00044310
• Kod UNSPSC: 41106305
• Identyfikator substancji w PubChem: 24900622
• NACRES: NA.52

Właściwości

• pochodzenie biologiczne: yeast (Candida Utilis)
• Poziom jakości: 300
• Próba: ≥95 (HPLC)
• Formularz: liquid
• stężenie: 100 mM in H₂O (adjusted to pH 7 with Trizma^®; base)
• kolor: colorless
• obecność zanieczyszczeń: DNase and RNase, none detected
• Warunki transportu: dry ice
• temp. przechowywania: −20°C
• ciąg SMILES: [Na+].[Na+].[Na+].O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP([O-])(=O)OP([O-])(=O)OP(O)([O-])=O)N2C=CC(=O)NC2=O
• InChI: 1S/C9H15N2O15P3.3Na/c12-5-1-2-11(9(15)10-5)8-7(14)6(13)4(24-8)3-23-28(19,20)26-29(21,22)25-27(16,17)18;;;/h1-2,4,6-8,13-14H,3H2,(H,19,20)(H,21,22)(H,10,12,15)(H2,16,17,18);;;/q;3*+1/p-3/t4-,6-,7-,8-;;;/m1.../s1
• Klucz InChI: MMJGIWFJVDOPJF-LLWADOMFSA-K
• informacje o genach: human ... P2RY2(5029) ; rat ... P2ry2(29597)

Opis

Zastosowanie

Uridine 5′-triphosphate trisodium salt solution has been used to increase the intracellular Ca²⁺ levels in rat primary tracheal epithelial cells. It has also been used as a nucleotide substrate to analyze the activity of MutT homologue 1 (MTH1).

Działania biochem./fizjol.

P2Y receptor agonist

UTP plays a crucial role in the process of transcription by participating in the synthesis of RNA. It is associated with glycogen synthesis, protein glycosylation, and membrane phospholipid biosynthesis. UTP is involved in the production of ATP, which is essential for metabolic reactions.

Uridine 5′-triphosphate (UTP) is released during nerve injury and acts as an agonist of the purinergic P2Y2 receptors present on the surface of Schwann cells.

Informacje prawne

Trizma is a registered trademark of Merck KGaA, Darmstadt, Germany

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Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 10 - Combustible liquids
• Klasa zagrożenia wodnego (WGK): WGK 3
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable