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F3393
Anti-Fibroblast Growth Factor-Basic (1-24) antibody produced in rabbit
fractionated antiserum, lyophilized powder
Synonim(y):
Anti-FGF2, Anti-bFGF
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About This Item
Polecane produkty
pochodzenie biologiczne
rabbit
Poziom jakości
białko sprzężone
unconjugated
forma przeciwciała
fractionated antiserum
rodzaj przeciwciała
primary antibodies
klon
polyclonal
Postać
lyophilized powder
reaktywność gatunkowa
human, bovine, rat
metody
immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable
indirect ELISA: suitable
western blot: 1:1,000
zanieczyszczenia
endotoxin, tested
numer dostępu UniProt
Zastosowanie
research pathology
temp. przechowywania
2-8°C
docelowa modyfikacja potranslacyjna
unmodified
informacje o genach
bovine ... FGF2(281161)
human ... FGF2(2247)
rat ... Fgf2(54250)
Opis ogólny
Fibroblast growth factor-basic (FGFb), also known as NUDT6 (nudix (nucleoside diphosphate linked moiety X)-type motif 6) is encoded by the gene mapped to human chromosome 4q28.1. The FGFb gene spanning 34271 bp on genomic DNA contains 16 exons and six introns. FGFb RNA transcripts are expressed in various human tissues including liver, thymus, spleen, peripheral blood leukocytes, heart skeletal muscle, testis, colon and kidney.
Immunogen
synthetic peptide sequence corresponding to bovine FGF2 (1-24).
Zastosowanie
Anti-Fibroblast Growth Factor-Basic (1-24) antibody produced in rabbit has been used in:
- immunohistochemistry
- immunostaining
- immunoblotting
Działania biochem./fizjol.
Fibroblast Growth Factor Basic (also known as bFGF) is a pleotropic cytokine that that is a potent mitogenic factor. On binding to its cognate receptor tyrosine kinase, FGFR, bFGF is capable of activation of pathways such as MAPK and PI3K and produce cellular effects in varied cell types. Fibroblast Growth Factor-basic is reported to induce proliferation of fibroblasts, differentiation, wound healing and regeneration, limb formation, tissue remodeling and angiogenesis.
Postać fizyczna
Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline.
Komentarz do analizy
Bioactivity: Anti-Fibroblast Growth Factor-Basic (1-24) caused a dose-dependent decrease in the mitogenic activity of FGF-Basic such that a final dilution of 1:50 neutralized the bioactivity of 1 unit of FGF Basic.
Oświadczenie o zrzeczeniu się odpowiedzialności
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Numer produktu
Opis
Cennik
Kod klasy składowania
11 - Combustible Solids
Klasa zagrożenia wodnego (WGK)
WGK 3
Temperatura zapłonu (°F)
Not applicable
Temperatura zapłonu (°C)
Not applicable
Środki ochrony indywidualnej
Eyeshields, Gloves, type N95 (US)
Certyfikaty analizy (CoA)
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