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Merck

D2629

Sigma-Aldrich

6-(Dimethylamino)purine

≥98%

Synonim(y):

6-DMAP, N6,N6-Dimethyladenine

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About This Item

Wzór empiryczny (zapis Hilla):
C7H9N5
Numer CAS:
Masa cząsteczkowa:
163.18
Beilstein:
7634
Numer WE:
Numer MDL:
Kod UNSPSC:
41106305
Identyfikator substancji w PubChem:
NACRES:
NA.51

pochodzenie biologiczne

synthetic (organic)

Poziom jakości

Próba

≥98%

Postać

powder

mp

259-262 °C (lit.)

rozpuszczalność

water: 50 mg/mL, clear to hazy, colorless to light yellow

temp. przechowywania

−20°C

ciąg SMILES

CN(C)c1ncnc2[nH]cnc12

InChI

1S/C7H9N5/c1-12(2)7-5-6(9-3-8-5)10-4-11-7/h3-4H,1-2H3,(H,8,9,10,11)

Klucz InChI

BVIAOQMSVZHOJM-UHFFFAOYSA-N

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Opis ogólny

6-(Dimethylamino)purine (6-DMAP) is a purine-based metabolite with two condensed heterocyclic rings and two methyl groups linked to the amino group of the purine unit of adenine.

Zastosowanie

6-(Dimethylamino)purine has been used:
  • as a supplement in GR-1 aa medium (bovine medium) for parthenogenetic activation of bovine oocytes to study its potential for embryo development
  • in the activation step during the production of nuclear transfer embryos
  • as a supplement in HCR2aa medium to activate interspecies embryos derived from interspecies somatic cell nuclear transfer (iSCNT) technique

Działania biochem./fizjol.

6-(Dimethylamino)purine (6-DMAP) is a protein kinase and cyclin-dependent kinase inhibitor. It acts as a secondary metabolite and mediates RNA modification. 6-DMAP is a potent cytokinetic inhibitor and is used in parthenogenesis and meiosis studies. It is also used to promote pronuclei formation in mammalian oocytes. 6-DMAP is a dual fluorescence molecule according to femtosecond fluorescence up-conversion spectroscopy studies.
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Kod klasy składowania

11 - Combustible Solids

Klasa zagrożenia wodnego (WGK)

WGK 3

Temperatura zapłonu (°F)

Not applicable

Temperatura zapłonu (°C)

Not applicable

Środki ochrony indywidualnej

Eyeshields, Gloves, type N95 (US)


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