CN406-05

Canine Osteoblasts: CnOb (Cryovial)

• Kod UNSPSC: 41106514
• NACRES: NA.81

Właściwości

• pochodzenie biologiczne: canine bone (normal)
• opakowanie: pkg of 500,000 cells
• producent / nazwa handlowa: Cell Applications, Inc
• tryb wzrostu: Adherent
• kariotyp: 2n = 78
• morfologia: osteoblast
• metody: cell culture | mammalian: suitable
• powiązane choroby: arthritis; osteoporosis
• Warunki transportu: dry ice
• temp. przechowywania: −196°C

Opis

Opis ogólny

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Canine osteoblasts provide an excellent model system for studies relevant to the skeletal system, including mechanisms of cancerogenesis.

Canine osteoblasts have been used to define a biomarker profile of canine osteosarcoma (Milovancev, 2013), elucidate the roles of oncogenic STAT3 (Fossey, 2009, 2011) and canonical Wnt signaling (Piskun, 2013) pathways, and to develop personalized osteosarcoma treatments by testing Src inhibitor dasatinib (Davis, 2013), procaspase-3 activating compound PAC-1 (Book, 2012), HSP90 inhibitor STA-1474 (McCleese, 2009) and STAT3 inhibitor LLL12 (Couto, 2012, 2013).

Characterization: Positive for bone mineralization.

Pochodzenie linii komórkowej

Bone

Zastosowanie

model for skeletal system research, signaling pathways, bone morphogenesis, gene expression, cell activation and proliferation, wound healing, bone formation and regeneration, treatment strategies, tissue engineering, in vitro bone models, mineralization, hormone treatments

Komponenty

Canine Osteoblast Basal Medium containing 10% FBS & 10% DMSO

Uwaga dotycząca przygotowania

• 1st passage, >500,000 cells in Canine Osteoblast Basal Medium containing 10% FBS & 10% DMSO
• Can be cultured at least 10 doublings

Rutyna subkultury

Please refer to the CnOb Culture Protocol.

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Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 11 - Combustible Solids
• Klasa zagrożenia wodnego (WGK): WGK 3
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable