905H-0

Cytokeratin 5 (EP1601Y) + Cytokeratin 14 (LL002)

Mouse and Rabbit Monoclonal Antibody

• Synonim(y): Cytokeratin 5 (EP1601Y) + Cytokeratin 14 (LL002) Mouse and Rabbit Monoclonal Antibody
• Kod UNSPSC: 12352203
• NACRES: NA.41

Właściwości

• pochodzenie biologiczne: mouse; rabbit
• Poziom jakości: 100; 500
• białko sprzężone: unconjugated
• forma przeciwciała: purified immunoglobulin
• rodzaj przeciwciała: primary antibodies
• klon: EP1601Y + LL002, monoclonal
• opis: For In Vitro Diagnostic Use in Select Regions (See Chart)
• Formularz: buffered aqueous solution
• reaktywność gatunkowa: human
• opakowanie: bottle of 1.0 mL predilute (905H-07); bottle of 7.0 mL predilute (905H-08)
• producent / nazwa handlowa: Cell Marque^™
• stężenie: 0.1-1.5 μg/mL (predilute)
• izotyp: IgG3; IgG
• Warunki transportu: wet ice
• temp. przechowywania: 2-8°C
• informacje o genach: human ... KRT5(3852)

Opis

Opis ogólny

Cytokeratin 5 is an intermediate filament protein of 58 kD molecular wt. amongst the cytokeratin family. It is a type II (basic) cytokeratin. Antibodies to this protein identify basal cells of squamous and glandular epithelia, myoepithelia, and mesothelium. Cytokeratin 14 is a 50 kD polypeptide found in basal cells of squamous epithelia, some glandular epithelia, myoepithelium, and mesothelial cells. Anti-Cytokeratin 5 has been useful in the differential diagnosis of metastatic carcinoma in the pleura versus epithelial mesothelioma. Almost all squamous cell carcinomas, half of transitional carcinomas, and many undifferentiated large cell carcinomas immunostain with CK5. Anti-CK14 has been demonstrated to be useful in differentiating squamous cell carcinomas from other epithelial tumors. Anti-CK5, along with anti-CK14, has found application in identifying the basaloid phenotype of breast carcinoma, a tumor with poor prognosis.

Jakość

IVD

IVD

IVD

RUO

Postać fizyczna

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Uwaga dotycząca przygotowania

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Inne uwagi

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Informacje prawne

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

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