451M-1

h-Caldesmon (hHCD) Mouse Monoclonal Antibody

• Kod UNSPSC: 12352203

Właściwości

• pochodzenie biologiczne: mouse
• Poziom jakości: 100; 500
• białko sprzężone: unconjugated
• forma przeciwciała: diluted ascites fluid
• rodzaj przeciwciała: primary antibodies
• klon: hHCD, monoclonal
• opis: For In Vitro Diagnostic Use in Select Regions
• Postać: buffered aqueous solution
• reaktywność gatunkowa: human
• opakowanie: vial of 0.1 mL concentrate (451M-14); vial of 0.1 mL concentrate Research Use Only (451M-14-RUO); vial of 0.5 mL concentrate (451M-15); vial of 1.0 mL concentrate (451M-16); vial of 1.0 mL concentrate Research Use Only (451M-16-RUO); vial of 1.0 mL pre-dilute Research Use Only (451M-17-RUO); vial of 1.0 mL pre-dilute ready-to-use (451M-17); vial of 7.0 mL pre-dilute ready-to-use (451M-18); vial of 7.0 mL pre-dilute ready-to-use Research Use Only (451M-18-RUO)
• producent / nazwa handlowa: Cell Marque^™
• metody: immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100 (concentrated)
• izotyp: IgG1
• kontrola: bladder, colon, leiomyoma, smooth muscle tumors, stomach
• Warunki transportu: wet ice
• temp. przechowywania: 2-8°C
• wizualizacja: cytoplasmic

Opis

Opis ogólny

Caldesmon is a protein that facilitates the regulation of cellular contraction through complexing with calmodulin, tropomyosin, and actin. Its high molecular weight isoform (h-caldesmon) has been identified to have restricted expression in visceral and vascular smooth muscle cells. In particular, strong expression of h-caldesmon has been observed in non-neoplastic uterine myometrium while being entirely absent in the endometrial layer. In spindle cell tumor pathology, overlapping immunohistochemical staining profiles between smooth muscle cells and myofibroblastic cells has not allowed for reliable identification of true smooth muscle tumors. Immunohistochemical detection of h-caldesmon has been demonstrated to aid in the distinguishing smooth muscle tumors, such as leiomyoma and leiomyosarcoma from myofibroblastic lesions, such as inflammatory myofibroblastic tumors and fibromatoses.

Jakość

IVD

IVD

IVD

RUO

Postać fizyczna

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.

Uwaga dotycząca przygotowania

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Inne uwagi

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Informacje prawne

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

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Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 12 - Non Combustible Liquids
• Klasa zagrożenia wodnego (WGK): WGK 2
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable