426R-1

STAT6 (EP325) Rabbit Monoclonal Primary Antibody

• Synonim(y): Signal Transducer and Activator of Transcription
• Kod UNSPSC: 12352203

Właściwości

• pochodzenie biologiczne: rabbit
• Poziom jakości: 100; 500
• białko sprzężone: unconjugated
• forma przeciwciała: culture supernatant
• rodzaj przeciwciała: primary antibodies
• klon: EP325, monoclonal
• opis: For In Vitro Diagnostic Use in Select Regions
• Postać: buffered aqueous solution
• reaktywność gatunkowa: human
• opakowanie: vial of 0.1 mL concentrate (426R-14); vial of 0.1 mL concentrate Research Use Only (426R-14-RUO); vial of 0.5 mL concentrate (426R-15); vial of 1.0 mL concentrate (426R-16); vial of 1.0 mL concentrate Research Use Only (426R-16-RUO); vial of 1.0 mL pre-dilute Research Use Only (426R-17-RUO); vial of 1.0 mL pre-dilute ready-to-use (426R-17); vial of 7.0 mL pre-dilute ready-to-use (426R-18); vial of 7.0 mL pre-dilute ready-to-use Research Use Only (426R-18-RUO)
• producent / nazwa handlowa: Cell Marque^™
• metody: immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100 (concentrated)
• izotyp: IgG
• kontrola: solitary fibrous tumor
• Warunki transportu: wet ice
• temp. przechowywania: 2-8°C
• wizualizacja: nuclear
• informacje o genach: human ... STAT6(6778)

Opis

Opis ogólny

STAT6, a member of the signal transducers and activators of transcription (STAT) family, has been found to form recurrent fusions with NAB2 on chromosome 12q13 in the majority of solitary fibrous tumors. Inactivated STAT6 can be found in the form of a dimer located in the cytoplasm. STAT6 and NAB2 fusion enables cytosolic STAT6 to migrate to the nucleus and thus allowing for detection in immunohistochemical assays. NAB2-STAT6 fusion transcriptions have been reported in the majority of solitary fibrous tumors but not in meningiomas, hemangioblastomas, schwannomas, and hemangiomas. This makes STAT6 a useful marker in distinguishing solitary fibrous tumors from other morphologically similar tumors.

Jakość

IVD

IVD

IVD

RUO

Postać fizyczna

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.

Uwaga dotycząca przygotowania

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Inne uwagi

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Informacje prawne

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

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Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 12 - Non Combustible Liquids
• Klasa zagrożenia wodnego (WGK): WGK 2
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable