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Key Documents

227M-9

Sigma-Aldrich

BCL6 (GI191E/A8) Mouse Monoclonal Antibody

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About This Item

Kod UNSPSC:
12352200
NACRES:
NA.41

pochodzenie biologiczne

mouse

Poziom jakości

100
500

białko sprzężone

unconjugated

forma przeciwciała

culture supernatant

rodzaj przeciwciała

primary antibodies

klon

GI191E/A8, monoclonal

opis

For In Vitro Diagnostic Use in Select Regions (See Chart)

Postać

buffered aqueous solution

reaktywność gatunkowa

human

opakowanie

vial of 0.1 mL concentrate (227M-94)
vial of 0.5 mL concentrate (227M-95)
bottle of 1.0 mL predilute (227M-97)
vial of 1.0 mL concentrate (227M-96)
bottle of 7.0 mL predilute (227M-98)

producent / nazwa handlowa

Cell Marque

metody

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500

kontrola

tonsil

Warunki transportu

wet ice

temp. przechowywania

2-8°C

wizualizacja

nuclear

informacje o genach

human ... BCL6(604)

Powiązane kategorie

Opis ogólny

BCL6 is a transcriptional regulator gene that codes for a 706-amino-acid nuclear zinc finger protein. In normal tissue, anti-BCL6 antibody shows strong nuclear staining in a subset of B-lymphocytes, mostly located in germinal centers (GC). BCL6 expression is usually present in follicular lymphomas, diffuse large B-cell lymphomas, and Burkitt lymphomas.

Jakość


IVD

IVD

IVD

RUO

Powiązanie

BCL6 Positive Control Slides, Product No. 227S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Postać fizyczna

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Uwaga dotycząca przygotowania

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Inne uwagi

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Informacje prawne

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany
This page may contain text that has been machine translated.

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Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.

Odwiedź Bibliotekę dokumentów

A Dogan et al.
The American journal of surgical pathology, 24(6), 846-852 (2000-06-08)
In this study the authors explored the value of immunostaining for follicular center B-cell markers, BCL-6 and CD10, in paraffin sections as a tool for the differential diagnosis of B-cell lymphomas. The cases studied comprised reactive lymphoid hyperplasia (RLH; n
A Carbone et al.
Blood, 90(6), 2445-2450 (1997-10-06)
The expression pattern of the BCL-6 transcription factor has been assessed in normal and neoplastic B-cell populations and in Hodgkin's disease. However, little is known about BCL-6 expression and its biological significance in T-cell neoplasms. In this study, a series
A Carbone et al.
Blood, 91(3), 747-755 (1998-02-03)
This study was aimed at defining the histogenesis of the pathologic spectrum of acquired immunodeficiency syndrome-related non-Hodgkin's lymphomas (AIDS-NHL), including AIDS-related small noncleaved cell lymphoma (AIDS-SNCCL), AIDS-related large noncleaved cell lymphoma (AIDS-LNCCL), AIDS-related large cell immunoblastic lymphoma plasmacytoid (AIDS-IBLP), and
José-Francisco García et al.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 54(1), 31-38 (2005-07-28)
Genetic immunization can be combined with hybridoma technology to generate high-affinity monoclonal antibodies (MAbs). A new anti-BCL-6 MAb (GI191E/A8) was produced by cloning full-length BCL-6 cDNA into a eukaryotic vector and delivering this into mouse epidermis using a helium gene
Antonino Carbone et al.
Human pathology, 41(5), 621-631 (2010-04-20)
Published in September 2008, the updated World Health Organization Classification of Tumors of Hematopoietic and Lymphoid Tissues introduces provisional borderline categories for lymphoma cases that demonstrate overlapping clinical, morphological, and/or immunophenotypic features between well-established entities. These overlapping features pose real

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