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Y0000878

Atropine

European Pharmacopoeia (EP) Reference Standard

Synonim(y):

Hyoscyamine, Tropine tropate, endo-(±)-α-(Hydroxymethyl)benzeneacetic acid 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester

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About This Item

Wzór empiryczny (zapis Hilla):
C17H23NO3
Numer CAS:
51-55-8
Masa cząsteczkowa:
289.37
Beilstein:
91260
Numer MDL:
MFCD00022622
Kod UNSPSC:
41116107
Identyfikator substancji w PubChem:
329831200
NACRES:
NA.24

klasa czystości

pharmaceutical primary standard

rodzina API

atropine

producent / nazwa handlowa

EDQM

Zastosowanie

pharmaceutical (small molecule)

format

neat

temp. przechowywania

2-8°C

ciąg SMILES

CN1[C@H]2CC[C@@H]1C[C@@H](C2)OC(=O)C(CO)c3ccccc3

InChI

1S/C17H23NO3/c1-18-13-7-8-14(18)10-15(9-13)21-17(20)16(11-19)12-5-3-2-4-6-12/h2-6,13-16,19H,7-11H2,1H3/t13-,14+,15+,16?

Klucz InChI

RKUNBYITZUJHSG-SPUOUPEWSA-N

informacje o genach

human ... CHRM1(1128) , CHRM2(1129) , CHRM3(1131)

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Opis ogólny

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Zastosowanie

Atropine EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Działania biochem./fizjol.

Competitive nonselective antagonist at central and peripheral muscarinic acetylcholine receptors.

Opakowanie

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Inne uwagi

Sales restrictions may apply.
This page may contain text that has been machine translated.

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Atropine for peak identification, European Pharmacopoeia (EP) Reference Standard

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Atropine impurity B, European Pharmacopoeia (EP) Reference Standard

PHR1379

Atropine Sulfate, Pharmaceutical Secondary Standard; Certified Reference Material

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BP689

Desmethyl benzatropine hydrochloride, British Pharmacopoeia (BP) Reference Standard

Piktogramy

Skull and crossbones
GHS06

Hasło ostrzegawcze

Danger

Zwroty wskazujące rodzaj zagrożenia

H300 + H330

Zwroty wskazujące środki ostrożności

P260 - P264 - P271 - P284 - P304 + P340 + P310 - P403 + P233

Klasyfikacja zagrożeń

Acute Tox. 2 Inhalation - Acute Tox. 2 Oral

Kod klasy składowania

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

Klasa zagrożenia wodnego (WGK)

WGK 3

Temperatura zapłonu (°F)

Not applicable

Temperatura zapłonu (°C)

Not applicable

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Certyfikaty analizy (CoA)

Lot/Batch Number

Sorry, we don't have COAs for this product available online at this time.

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Baptiste Berton et al.
Pharmaceutics, 12(8) (2020-08-23)
Myopia is an ophthalmic condition affecting more than 1/5th of the world population, especially children. Low-dose atropine eyedrops have been shown to limit myopia evolution during treatment. However, there are currently no commercial industrial forms available and there is little
Joanna Kur et al.
The Journal of physiology, 592(3), 491-504 (2013-11-28)
Purinergic control of vascular tone in the CNS has been largely unexplored. This study examines the contribution of endogenous extracellular ATP, acting on vascular smooth muscle cells, in controlling vascular tone in the in vivo rat retina. Retinal vessels were
M M McCarron et al.
Pediatrics, 87(5), 694-700 (1991-05-01)
Eight pediatric accidental overdoses of diphenoxylate-atropine (Lomotil) are reported, and 28 literature cases are reviewed. This overdose is primarily an opioid intoxication, occasionally associated with atropine toxicity. Only 6 of 36 children showed signs of atropine overdose (central nervous system
Yossi Rosman et al.
Annals of internal medicine, 160(9), 644-648 (2014-05-07)
On the night of 21 August 2013, sarin was dispersed in the eastern outskirts of Damascus, killing 1400 civilians and severely affecting thousands more. This article aims to delineate the clinical presentation and management of a mass casualty event caused
Ariane Rossi et al.
Anesthesia and analgesia, 119(4), 947-955 (2014-08-05)
Cerebral cholinergic transmission plays a key role in cognitive function, and anticholinergic drugs administered during the perioperative phase are a hypothetical cause of postoperative cognitive dysfunction (POCD). We hypothesized that a perioperative increase in serum anticholinergic activity (SAA) is associated
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