X4251

XTT sodium salt

analytical standard, ≥90%

• Synonim(y): 2,3-Bis(2-methoxy-4-nitro-5-sulfophenyl)-2H-tetrazolium-5-carboxanilide inner salt
• Wzór empiryczny (zapis Hilla): C₂₂H₁₆N₇NaO₁₃S₂
• Numer CAS: 111072-31-2
• Masa cząsteczkowa: 673.52
• Numer MDL: MFCD00083517
• Kod UNSPSC: 41116107
• Identyfikator substancji w PubChem: 329830806
• NACRES: NA.24

Właściwości

• klasa czystości: analytical standard
• Poziom jakości: 100
• Próba: ≥90%
• metody: HPLC: suitable; gas chromatography (GC): suitable
• Zastosowanie: forensics and toxicology; pharmaceutical (small molecule)
• format: neat
• temp. przechowywania: 2-8°C
• ciąg SMILES: [Na+].COc1cc(c(cc1-n2nc(n[n+]2-c3cc(c(cc3OC)[N+]([O-])=O)S([O-])(=O)=O)C(=O)Nc4ccccc4)S([O-])(=O)=O)[N+]([O-])=O
• InChI: 1S/C22H17N7O13S2.Na/c1-41-17-8-15(28(31)32)19(43(35,36)37)10-13(17)26-24-21(22(30)23-12-6-4-3-5-7-12)25-27(26)14-11-20(44(38,39)40)16(29(33)34)9-18(14)42-2;/h3-11H,1-2H3,(H2-,23,30,35,36,37,38,39,40);/q;+1/p-1
• Klucz InChI: JACYMBNQPPWQML-UHFFFAOYSA-M

Opis

Zastosowanie

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Useful in AIDS and cancer testing.

XTT has been used in conjunction with phenazine methosulfate (PMS) to screen human cancer cell lines. The tetrazolium dye has also been used to study fungal cell damage, in testing antimicrobial susceptibility of staphylococci, and in Candida biofilm research. Limitations to the XTT assay have been reported.

Zasada

In living cells, XTT is metabolically reduced to produce a colorimetric, water-soluble formazan product.

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Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 4.1A - Other explosive hazardous materials
• Klasa zagrożenia wodnego (WGK): WGK 3
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable
• Środki ochrony indywidualnej: Eyeshields, Gloves, type N95 (US)