PHR1494

Pilocarpine Nitrate

Pharmaceutical Secondary Standard; Certified Reference Material

• Synonim(y): Pilocarpine nitrate salt
• Wzór empiryczny (zapis Hilla): C₁₁H₁₆N₂O₂ · HNO₃
• Numer CAS: 148-72-1
• Masa cząsteczkowa: 271.27
• Beilstein: 4171406
• Numer WE: 205-723-7
• Numer MDL: MFCD00078497
• Kod UNSPSC: 41116107
• Identyfikator substancji w PubChem: 329823416
• NACRES: NA.24

Właściwości

• klasa czystości: certified reference material; pharmaceutical secondary standard
• Poziom jakości: 300
• agency: traceable to BP 503; traceable to Ph. Eur. P1700000; traceable to USP 1539009
• rodzina API: pilocarpine
• Certyfikat analizy: current certificate can be downloaded
• opakowanie: pkg of 500 mg
• metody: HPLC: suitable; gas chromatography (GC): suitable
• Zastosowanie: pharmaceutical (small molecule)
• format: neat
• temp. przechowywania: 2-30°C
• ciąg SMILES: O[N+]([O-])=O.CC[C@H]1[C@H](COC1=O)Cc2cncn2C
• InChI: 1S/C11H16N2O2.HNO3/c1-3-10-8(6-15-11(10)14)4-9-5-12-7-13(9)2;2-1(3)4/h5,7-8,10H,3-4,6H2,1-2H3;(H,2,3,4)/t8-,10-;/m0./s1
• Klucz InChI: PRZXEPJJHQYOGF-GNAZCLTHSA-N
• informacje o genach: human ... CHRM1(1128) , CHRM3(1131)

Opis

Opis ogólny

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Pilocarpine Nitrate is a naturally occurring cholinomimetic drug, exhibiting nicotinic and muscarinic properties. It is widely used for controlling intraocular pressure in glaucoma, immediate relief of mydriasis, and to reverse mydriasis caused by cycloplegic agents.

Zastosowanie

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Działania biochem./fizjol.

Nonselective muscarinic acetylcholine receptor agonist; used to produce an experimental model of epilepsy.

Komentarz do analizy

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Inne uwagi

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Przypis

To see an example of a Certificate of Analysis for this material enter LRAA3042 in the slot below. This is an example certificate only and may not be the lot that you receive.

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Informacja o środkach bezpieczeństwa

• Piktogramy: GHS03,GHS06
• Hasło ostrzegawcze: Danger
• Zwroty wskazujące rodzaj zagrożenia: H272,H302,H330
• Zwroty wskazujące środki ostrożności: P210 - P220 - P260 - P264 - P301 + P312 - P304 + P340 + P310
• Klasyfikacja zagrożeń: Acute Tox. 2 Inhalation - Acute Tox. 4 Oral - Ox. Sol. 2
• Kod klasy składowania: 5.1B - Oxidizing hazardous materials
• Klasa zagrożenia wodnego (WGK): WGK 3
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable