PHL82530

(−)-Englerin A

phyproof^® Reference Substance

• Wzór empiryczny (zapis Hilla): C₂₆H₃₄O₆
• Numer CAS: 1094250-15-3
• Masa cząsteczkowa: 442.54
• Kod UNSPSC: 41116107

Właściwości

• klasa czystości: primary reference standard
• linia produktu: phyproof^® Reference Substance
• Próba: ≥95.0% (HPLC)
• producent / nazwa handlowa: PhytoLab
• Zastosowanie: food and beverages
• format: neat

Opis

Opis ogólny

This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG

Zastosowanie

• Englerin A as a Potent Selective Inhibitor of Renal Cancer: Englerin A has demonstrated remarkable efficacy in inducing cytotoxicity in renal cancer cells through the hyperphosphorylation of Hsp27 and as a promising antitumor agent in cancer pharmacotherapy (Neo et al., 2022).


• Natural Product TRPC4 Activator: Englerin A′s role in inhibiting T-type voltage-gated calcium channels showcases its unique mechanism of action as a natural product activator of TRPC4/TRPC5 ion channels, offering new avenues for therapeutic interventions in cancer biology (Wardas et al., 2023).

Informacje prawne

phyproof is a registered trademark of PhytoLab GmbH & Co. KG

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Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 11 - Combustible Solids
• Klasa zagrożenia wodnego (WGK): WGK 3
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable