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Sigma-Aldrich

Glyceryl triacetate

≥99.0% (GC)

Synonim(y):

1,2,3-Triacetoxypropane, 1,2,3-Triacetylglycerol, Glycerol triacetate, Triacetin

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About This Item

Wzór liniowy:
(CH3COOCH2)2CHOCOCH3
Numer CAS:
102-76-1
Masa cząsteczkowa:
218.20
Beilstein:
1792353
Numer WE:
203-051-9
Numer MDL:
MFCD00008716
Kod UNSPSC:
12352211
Identyfikator substancji w PubChem:
329769862
NACRES:
NA.25

Poziom jakości

200

Próba

≥99.0% (GC)

Postać

liquid

współczynnik refrakcji

n20/D 1.431

tw

258-260 °C (lit.)

gęstość

1.158 g/mL at 20 °C

typ lipidu

saturated FAs

ciąg SMILES

CC(=O)OCC(COC(C)=O)OC(C)=O

InChI

1S/C9H14O6/c1-6(10)13-4-9(15-8(3)12)5-14-7(2)11/h9H,4-5H2,1-3H3

Klucz InChI

URAYPUMNDPQOKB-UHFFFAOYSA-N

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Zastosowanie


  • Epigenetic priming targets tumor heterogeneity to shift transcriptomic phenotype of pancreatic ductal adenocarcinoma towards a Vitamin D susceptible state.: This groundbreaking study utilizes glyceryl triacetate as part of an epigenetic priming strategy to sensitize pancreatic ductal adenocarcinoma to Vitamin D, marking a significant advancement in cancer treatment modalities (He et al., 2024).

  • Glyceryl triacetate promotes blood-brain barrier recovery after ischemic stroke through lipogenesis-mediated IL-33 in mice.: Research demonstrates glyceryl triacetate′s effectiveness in enhancing blood-brain barrier repair post-ischemic stroke via lipogenesis pathways, offering insights into novel stroke recovery treatments (Wei et al., 2023).

  • Development of A Nanostructured Lipid Carrier-Based Drug Delivery Strategy for Apigenin: Experimental Design Based on CCD-RSM and Evaluation against NSCLC In Vitro.: This study details the formulation of a nanostructured lipid carrier incorporating glyceryl triacetate, optimized for delivering apigenin to combat non-small cell lung cancer, emphasizing the potential of glyceryl triacetate in targeted therapy applications (Wang et al., 2023).

  • Are New Phthalate Ester Substitutes Safer than Traditional DBP and DiBP Comparative Endocrine-Disrupting Analyses on Zebrafish Using In Vivo, Transcriptome, and In Silico Approaches.: Investigating glyceryl triacetate as a safer alternative to traditional phthalate esters, this study explores its lower endocrine-disrupting effects, contributing to safer industrial and pharmaceutical applications (Tan et al., 2023).

  • Glyceryl triacetate feeding in mice increases plasma acetate levels but has no anticonvulsant effects in acute electrical seizure models.: This research evaluates the biochemical impact of glyceryl triacetate on plasma acetate levels, providing valuable data on its metabolic effects despite a lack of anticonvulsant properties in specific seizure models (Xu et al., 2022).


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Kod klasy składowania

10 - Combustible liquids

Klasa zagrożenia wodnego (WGK)

WGK 1

Temperatura zapłonu (°F)

298.4 °F - closed cup

Temperatura zapłonu (°C)

148 °C - closed cup

Środki ochrony indywidualnej

Eyeshields, Gloves

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Certyfikaty analizy (CoA)

Lot/Batch Number
STBK6200
STBJ6199
STBH5774
STBG8286
BCBN6413V

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Journal of agricultural and food chemistry, 57(23), 11349-11353 (2009-11-07)
Citral is widely used in the beverage, food, and fragrance industries for its characteristic flavor profile. However, it chemically degrades over time in aqueous solutions due to an acid-catalyzed reaction, which leads to loss of desirable flavor notes and formation
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Journal of agricultural and food chemistry, 59(10), 5738-5745 (2011-04-26)
An oral colon-targeting controlled release system based on resistant starch acetate (RSA) as a film-coating material was developed. The RSA was successfully synthesized, and its digestion resistibility could be improved by increasing the degree of substitution (DS), which was favorable
Nilufer Yuksel et al.
International journal of pharmaceutics, 404(1-2), 102-109 (2010-11-26)
The purpose of this study was to form indomethacin (IND)-loaded poly(methyl methacrylate) (PMMA) microspheres having an extended drug release profile over a period of 24h. Microspheres were prepared by solvent evaporation method using sucrose stearate as a droplet stabilizer. When
Reeval Segel et al.
Molecular genetics and metabolism, 103(3), 203-206 (2011-04-09)
Canavan disease (CD MIM#271900) is a rare autosomal recessive neurodegenerative disorder presenting in early infancy. The course of the disease is variable, but it is always fatal. CD is caused by mutations in the ASPA gene, which codes for the
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