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Key Documents
17849
Enrofloxacin
≥99.0%
Synonim(y):
Baytril
Zaloguj sięWyświetlanie cen organizacyjnych i kontraktowych
About This Item
Wzór empiryczny (zapis Hilla):
C19H22FN3O3
Numer CAS:
Masa cząsteczkowa:
359.39
Beilstein:
5307824
Numer MDL:
Kod UNSPSC:
41116105
Identyfikator substancji w PubChem:
NACRES:
NA.21
Polecane produkty
Poziom jakości
Próba
≥99.0%
99.0-101.0% (dried substance)
Postać
powder or crystals
spektrum działania antybiotyku
Gram-negative bacteria
Gram-positive bacteria
Tryb działania
DNA synthesis | interferes
enzyme | inhibits
ciąg SMILES
CCN1CCN(CC1)c2cc3N(C=C(C(O)=O)C(=O)c3cc2F)C4CC4
InChI
1S/C19H22FN3O3/c1-2-21-5-7-22(8-6-21)17-10-16-13(9-15(17)20)18(24)14(19(25)26)11-23(16)12-3-4-12/h9-12H,2-8H2,1H3,(H,25,26)
Klucz InChI
SPFYMRJSYKOXGV-UHFFFAOYSA-N
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Opis ogólny
Chemical structure: fluoroquinolone
Enrofloxacin is a veterinary fluoroquinolone (FQ) antibiotic with broad-spectrum antimicrobial activity. FQ drugs chelate to iron with high affinity. This chelation leads to inhibition of Fe(II)-dependent dioxygenases involved in the regulation of epigenetic control, collagen maturation, and HIF (hypoxia-inducible factor) degradation. The side effects associated with FQ drugs are renal toxicity and tendinopathy. Enrofloxacin is used in aquaculture and its use may cause an increase in the growth of antibiotic resistant microbes in an aquatic environment. The drug may have negative effects on public health and environment.
Zastosowanie
Enrofloxacin has been used:
- to investigate the pathological mechanisms resulting from the toxicity of fluoroquinolones in mammalian cells
- to prepare a standard solution with 50% acetonitrile in a study to analyze illegal fish drugs used in aquaculture by employing surface-enhanced Raman spectroscopy (SERS)
- as an analyte in a chemiluminescence reagent system
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Hasło ostrzegawcze
Danger
Zwroty wskazujące rodzaj zagrożenia
Zwroty wskazujące środki ostrożności
Klasyfikacja zagrożeń
Acute Tox. 4 Oral - Resp. Sens. 1 - Skin Sens. 1
Kod klasy składowania
11 - Combustible Solids
Klasa zagrożenia wodnego (WGK)
WGK 3
Środki ochrony indywidualnej
Eyeshields, Gloves, type N95 (US)
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