MABS62

Anti-GREB1 Antibody, clone GREB1Ab

clone GREB1Ab, from mouse

• Synonim(y): growth regulation by estrogen in breast cancer 1, Gene regulated in breast cancer 1 protein, protein GREB1, gene regulated by estrogen in breast cancer protein
• Kod UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Właściwości

• pochodzenie biologiczne: mouse
• Poziom jakości: 100
• forma przeciwciała: purified immunoglobulin
• rodzaj przeciwciała: primary antibodies
• klon: GREB1Ab, monoclonal
• reaktywność gatunkowa: human
• metody: immunocytochemistry: suitable; immunohistochemistry: suitable; western blot: suitable
• izotyp: IgG1κ
• numer dostępu NCBI: NP_055483
• numer dostępu UniProt: Q4ZG55
• Warunki transportu: wet ice
• docelowa modyfikacja potranslacyjna: unmodified
• informacje o genach: human ... GREB1(9687)

Opis

Opis ogólny

GREB1, also known as gene regulated in breast cancer protein 1 is shown to be involved in the proliferation of breast cancer cells, controlled by estrogen. GREB1 has the potential to be a clinical marker for response to endocrine therapy and a therapeutic target. GREB1 also may be the regulator for prostate cancer.

Immunogen

Recombinant protein corresponding to human GREB1.

Zastosowanie

Immunohistochemistry Analysis: 1:600 dilution from a previous lot detected GREB1 in prostate tissue.

Immunocytochemistry Analysis: A previous lot was used by an independent laboratory in IP. (Hnatyszyn, H., et al. 2009). Breast Cancer Res Treat
DOI 10.1007/s10549-009-0584-x.)

Research Category
Signaling

Apoptosis & Cancer

Research Sub Category
Hormones & Receptors

This Anti-GREB1 Antibody, clone GREB1Ab is validated for use in WB, IH, IC for the detection of GREB1.

Jakość

Evaluated by Western Blot in MCF-7 cell lysate.

Western Blot Analysis: 0.5 µg/mL of this antibody detected GREB1 on 10 µg of MCF-7 cell lysate.

Opis wartości docelowych

~ 216 kDa observed. Uncharacterized bands may be observed in some lysates.

Postać fizyczna

Format: Purified

Protein G

Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Przechowywanie i stabilność

Stable for 1 year at 2-8°C from date of receipt.

Komentarz do analizy

Control
MCF-7 cell lysate

Inne uwagi

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Oświadczenie o zrzeczeniu się odpowiedzialności

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 12 - Non Combustible Liquids
• Klasa zagrożenia wodnego (WGK): WGK 1
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable