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MAB362

Sigma-Aldrich

Anti-MAP1 Antibody, clone HM-1

ascites fluid, clone HM-1, Chemicon®

Synonim(y):

Microtubule-Associated Protein

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About This Item

Kod UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41
klon:
HM-1, monoclonal
application:
ICC
IHC
WB
reaktywność gatunkowa:
rat, human, mouse
metody:
immunocytochemistry: suitable
immunohistochemistry: suitable
western blot: suitable
citations:
5

pochodzenie biologiczne

mouse

Poziom jakości

forma przeciwciała

ascites fluid

rodzaj przeciwciała

primary antibodies

klon

HM-1, monoclonal

reaktywność gatunkowa

rat, human, mouse

producent / nazwa handlowa

Chemicon®

metody

immunocytochemistry: suitable
immunohistochemistry: suitable
western blot: suitable

izotyp

IgG1

numer dostępu NCBI

numer dostępu UniProt

Warunki transportu

dry ice

docelowa modyfikacja potranslacyjna

unmodified

informacje o genach

human ... MAP1A(4130)

Specyficzność

Reacts specifically with MAP1 (also known as MAP 1a) on immunoblots of whole brain homogenate proteins. Shows selective staining of neurons and stronger staining of axons and dendrites in immunohistochemistry staining of brain tissue. Stains both the cell bodies and dendritic trees. No cross-reactivity observed to other MAPs or tubulin.

Immunogen

Rat brain microtubule-associated protein.

Zastosowanie

Detect MAP1 using this Anti-MAP1 Antibody, clone HM-1 validated for use in WB, IC, IH.
Immunoblotting at 1:500 using fresh rat brain extract or enriched microtubule protein preparation.

Immunocytochemistry

Optimal working dilutions must be determined by end user.
Research Category
Neuroscience
Research Sub Category
Neuronal & Glial Markers

Postać fizyczna

Ascites fluid. Liquid containing 15mM sodium azide.

Przechowywanie i stabilność

Maintain at -20°C in undiluted aliquots for up to 12 months after date of receipt. Avoid repeated freeze/thaw cycles.

During shipment, small volumes of antibody will occasionally become entrapped in the seal of the product vial. For antibodies with volumes of 200 μL or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container′s cap.

Informacje prawne

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Oświadczenie o zrzeczeniu się odpowiedzialności

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Kod klasy składowania

12 - Non Combustible Liquids

Klasa zagrożenia wodnego (WGK)

nwg

Temperatura zapłonu (°F)

Not applicable

Temperatura zapłonu (°C)

Not applicable


Certyfikaty analizy (CoA)

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Masz już ten produkt?

Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.

Odwiedź Bibliotekę dokumentów

R M Douglas et al.
Neuroscience, 139(4), 1249-1261 (2006-03-29)
Large-conductance voltage- and calcium-sensitive channels are known to be expressed in the plasmalemma of central neurons; however, recent data suggest that large-conductance voltage- and calcium-sensitive channels may also be present in mitochondrial membranes. To determine the subcellular localization and distribution
G Huber et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 4(1), 151-160 (1984-01-01)
The distribution of microtubule-associated proteins (MAPs) 1 and 2 in rat brain was studied using monoclonal antibodies. Immunochemical staining showed that both MAP1 and MAP2 are present only in neurons and both are highly concentrated in dendrites compared to axons.
Erin M Masucci et al.
Molecular biology of the cell, mbcE21100480-mbcE21100480 (2021-10-28)
Microtubules establish the directionality of intracellular transport by kinesins and dynein through polarized assembly, but it remains unclear how directed transport occurs along microtubules organized with mixed polarity. We investigated the ability of the plus-end directed kinesin-4 motor KIF21B to
Lihai Zhang et al.
Toxicological sciences : an official journal of the Society of Toxicology, 117(1), 180-189 (2010-06-18)
2,5-Hexanedione (HD) intoxication is associated with axon atrophy that might be responsible for the characteristic gait abnormalities, hindlimb skeletal muscle weakness and other neurological deficits that accompany neurotoxicity. Although previous mechanistic research focused on neurofilament triplet proteins (NFL, NFM, NFH)

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