MAB312RX
Anti-Neuron Cell Surface Antigen Antibody, clone A2B5-105 (7), Alexa Fluor™ 488
clone A2B5-105 (7), Chemicon®, from mouse
Synonim(y):
A2B5
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About This Item
Kod UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Polecane produkty
pochodzenie biologiczne
mouse
Poziom jakości
białko sprzężone
ALEXA FLUOR™ 488
forma przeciwciała
purified immunoglobulin
rodzaj przeciwciała
primary antibodies
klon
A2B5-105 (7), monoclonal
reaktywność gatunkowa
mouse, chicken, human, rat
producent / nazwa handlowa
Chemicon®
metody
immunocytochemistry: suitable
immunohistochemistry: suitable
izotyp
IgM
Warunki transportu
wet ice
docelowa modyfikacja potranslacyjna
unmodified
Specyficzność
The antibody recognizes an epitope common to silaogangliosides and sulfatides from the plasma membranes of neurons, and neuroendocrine and glial cells. Anti-A2B5 has been used to specifically stain:
· Neurofibrillary tangles in the post-mortem brain tissue of patients with a confirmed diagnosis of Alzheimer′s disease (Majocha et al., 1989)
· Neurons of chicken retina, brain, spinal cord, and dorsal root ganglia (Schnitzer & Schachner, 1982; Eisenbarth et al., 1979.
· Rat striatal nerve terminals [synaptosomes (Wolf & Kapatos, 1989].
· Neuroblastoma cells in man (Oppedal et al., 1989; Coakham et al., 1985).
· Rat insulinoma cells and pancreatic islets cells (Shimizu et al., 1983; Bartholomeusz et al., 1989).
· Human and rat thymic epithelial cells (Haynes, et al., 1988).
· Cells involved in gliogenesis (Bottenstein et al., 1988; Suzumura & slerberg, 1989).
· Oligodendrocytes and astrocytes, type II (Dubois-Dalcq et al., 1990).
· Neurofibrillary tangles in the post-mortem brain tissue of patients with a confirmed diagnosis of Alzheimer′s disease (Majocha et al., 1989)
· Neurons of chicken retina, brain, spinal cord, and dorsal root ganglia (Schnitzer & Schachner, 1982; Eisenbarth et al., 1979.
· Rat striatal nerve terminals [synaptosomes (Wolf & Kapatos, 1989].
· Neuroblastoma cells in man (Oppedal et al., 1989; Coakham et al., 1985).
· Rat insulinoma cells and pancreatic islets cells (Shimizu et al., 1983; Bartholomeusz et al., 1989).
· Human and rat thymic epithelial cells (Haynes, et al., 1988).
· Cells involved in gliogenesis (Bottenstein et al., 1988; Suzumura & slerberg, 1989).
· Oligodendrocytes and astrocytes, type II (Dubois-Dalcq et al., 1990).
Immunogen
Embryonic chicken retinal cells
Zastosowanie
Anti-Neuron Cell Surface Antigen Antibody, clone A2B5-105 (7), Alexa Fluor 488 detects level of Neuron Cell Surface Antigen & has been published & validated for use in IC, IH.
Immunocytochemistry
Immunohistochemistry: 1:30
Optimal working dilutions must be determined by end user.
Immunohistochemistry: 1:30
Optimal working dilutions must be determined by end user.
Research Category
Neuroscience
Neuroscience
Research Sub Category
Neuronal & Glial Markers
Neuronal & Glial Markers
Postać fizyczna
Purified immunoglobulin conjugated to Alexa Fluor™ 488. Liquid in Phosphate buffer with 15 mg/mL BSA as a stabilizer and 0.1% sodium azide.
Przechowywanie i stabilność
Maintain at 2-8°C in undiluted aliquots in the dark for up to 6 months after date of receipt.
Inne uwagi
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Informacje prawne
ALEXA FLUOR is a trademark of Life Technologies
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Oświadczenie o zrzeczeniu się odpowiedzialności
Alexa Fluor™ is a registered trademark of Molecular Probes, Inc.
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Kod klasy składowania
12 - Non Combustible Liquids
Klasa zagrożenia wodnego (WGK)
WGK 2
Temperatura zapłonu (°F)
Not applicable
Temperatura zapłonu (°C)
Not applicable
Certyfikaty analizy (CoA)
Poszukaj Certyfikaty analizy (CoA), wpisując numer partii/serii produktów. Numery serii i partii można znaleźć na etykiecie produktu po słowach „seria” lub „partia”.
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Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.
The effect of TGF-beta2 on elastin, type VI collagen, and components of the proteolytic degradation system in human optic nerve astrocytes.
Neumann, Carolin, et al.
Investigative Ophthalmology & Visual Science, 49, 1464-1472 (2008)
Pancreatic islet A2B5- and 3G5-reactive gangliosides are markers of differentiation in rat insulinoma cells.
Bartholomeusz, R K, et al.
Endocrinology, 124, 2680-2685 (1989)
Flow cytometric analysis of rat striatal nerve terminals
Wolf, M E and Kapatos, G
The Journal of Neuroscience, 9, 94-105 (1989)
B F Haynes et al.
The Journal of clinical investigation, 71(1), 9-14 (1983-01-01)
Using a monoclonal antibody (A2B5), which binds to GQ ganglioside, and tetanus toxin, which binds to GD and GT gangliosides, distinct regions of human and rodent thymic epithelial cells have been identified. The lymphoid elements of the thymus do not
Bone marrow examination in neuroblastoma patients: a morphologic, immunocytochemical, and immunohistochemical study
Oppedal, B R, et al
Human Pathology, 20, 800-805 (1989)
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