MAB1852
Anti-Macrophages/Monocytes Antibody, clone MOMA-2
clone MOMA-2, Chemicon®, from rat
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About This Item
Kod UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Polecane produkty
pochodzenie biologiczne
rat
Poziom jakości
forma przeciwciała
purified immunoglobulin
rodzaj przeciwciała
primary antibodies
klon
MOMA-2, monoclonal
reaktywność gatunkowa
mouse
producent / nazwa handlowa
Chemicon®
metody
flow cytometry: suitable
immunohistochemistry: suitable
izotyp
IgG2b
Warunki transportu
wet ice
docelowa modyfikacja potranslacyjna
unmodified
Powiązane kategorie
Specyficzność
Recognizes an intracellular antigen of mouse macrophages and monocytes. It reacts strongly with macrophages in lymphoid organs such as tingible body macrophages and macrophages in T cell dependent areas and is extremely useful in immunohistochemistry. Reacts on all mouse strains tested.
Zastosowanie
Detect Macrophages/Monocytes using this Anti-Macrophages/Monocytes Antibody, clone MOMA-2 validated for use in FC, IH.
Flow Cytometry: membrane permeabilization is recommended for this application.
Immunohistology: FRESH frozen sections at 1:25. The epitope recognized by MAB1852 is formaline sensitive. Fixation in fresh, acetone at 4°C or colder is strongly recommended. Specimens must be completely air dried after acetone fixation. Formalin or PFA fixation is not recommended.
Because of the lower titer, enhanced detection systems such as our poly-HRP secondaries or biotin labelled secondary antibodies followed by SA-FITC are recommended.
Optimal working dilutions must be determined by end user.
Immunohistology: FRESH frozen sections at 1:25. The epitope recognized by MAB1852 is formaline sensitive. Fixation in fresh, acetone at 4°C or colder is strongly recommended. Specimens must be completely air dried after acetone fixation. Formalin or PFA fixation is not recommended.
Because of the lower titer, enhanced detection systems such as our poly-HRP secondaries or biotin labelled secondary antibodies followed by SA-FITC are recommended.
Optimal working dilutions must be determined by end user.
Research Category
Inflammation & Immunology
Inflammation & Immunology
Research Sub Category
Inflammation & Autoimmune Mechanisms
Inflammation & Autoimmune Mechanisms
Postać fizyczna
Format: Purified
Protein A Purified mouse immunoglobulin in 10 mM sodium phosphate buffer (pH 7.4), 0.15 M NaCl, and 0.1% sodium azide as a preservative..
Protein A purified
Przechowywanie i stabilność
Maintain for 1 year at 2–8°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Komentarz do analizy
Control
Macrophages, monocytes, lymphoid organs
Macrophages, monocytes, lymphoid organs
Inne uwagi
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Informacje prawne
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Oświadczenie o zrzeczeniu się odpowiedzialności
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Kod klasy składowania
12 - Non Combustible Liquids
Klasa zagrożenia wodnego (WGK)
WGK 2
Temperatura zapłonu (°F)
Not applicable
Temperatura zapłonu (°C)
Not applicable
Certyfikaty analizy (CoA)
Poszukaj Certyfikaty analizy (CoA), wpisując numer partii/serii produktów. Numery serii i partii można znaleźć na etykiecie produktu po słowach „seria” lub „partia”.
Masz już ten produkt?
Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.
Macrophages in T and B cell compartments and other tissue macrophages recognized by monoclonal antibody MOMA-2. An immunohistochemical study.
Kraal, G, et al.
Scandinavian Journal of Immunology, 26, 653-661 (1987)
Morphologic and electroretinographic phenotype of SR-BI knockout mice after a long-term atherogenic diet.
Provost AC, Vede L, Bigot K, Keller N, Tailleux A, Jais JP, Savoldelli M, Ameqrane I et al.
Investigative Ophthalmology & Visual Science null
Cannabinoid receptor type 2 (CB2) deficiency alters atherosclerotic lesion formation in hyperlipidemic Ldlr-null mice.
Courtney D Netherland,Theresa G Pickle,Alicia Bales,Douglas P Thewke
Atherosclerosis null
Yujiao Zhang et al.
Nature communications, 14(1), 4622-4622 (2023-08-02)
Caspase recruitment-domain containing protein 9 (CARD9) is a key signaling pathway in macrophages but its role in atherosclerosis is still poorly understood. Global deletion of Card9 in Apoe-/- mice as well as hematopoietic deletion in Ldlr-/- mice increases atherosclerosis. The
Johannes Schödel et al.
Atherosclerosis, 206(2), 383-389 (2009-04-11)
We previously reported that deletion of brain type neuronal nitric oxide synthase-alpha (nNOS-alpha) accelerates atherosclerosis in apolipoproteinE (apoE) knockout (ko) mice. The regulation of nNOS expression is complex, involving the generation of mRNA splice variants. The current study investigates occurrence
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