MAB1567
Anti-Myelin Associated Glycoprotein Antibody, clone 513
clone 513, Chemicon®, from mouse
Synonim(y):
MAG
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About This Item
Kod UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Polecane produkty
pochodzenie biologiczne
mouse
Poziom jakości
forma przeciwciała
purified immunoglobulin
rodzaj przeciwciała
primary antibodies
klon
513, monoclonal
reaktywność gatunkowa
mouse, rat, frog, bovine, chicken, human
producent / nazwa handlowa
Chemicon®
metody
immunocytochemistry: suitable
immunohistochemistry: suitable
western blot: suitable
izotyp
IgG1
numer dostępu NCBI
numer dostępu UniProt
Warunki transportu
dry ice
docelowa modyfikacja potranslacyjna
unmodified
informacje o genach
human ... MAG(4099)
Opis ogólny
Myelin-associated glycoprotein (MAG),a member of the immunoglobulin superfamily, is a membrane glycoprotein of 100 kDa, and is thought to be involved in the process of myelination. Axonal regeneration in the adult central nervous system (CNS) is limited by two proteins in myelin, Nogo and MAG. MAG has been implicated in the inhibition of nerve regeneration in the CNS.
Specyficzność
Detects Myelin Associated Glycoprotein (MAG) in immunohistochemistry on frozen sections, immunocytochemistry and Western blot (under non-reducing conditions). MAB1567 is useful for myelinogenesis and multiple sclerosis studies.
Immunogen
L2 epitope carrying glycoprotein extract of 1-2 day old chicken brain.
Zastosowanie
Detect Myelin Associated Glycoprotein using this Anti-Myelin Associated Glycoprotein Antibody, clone 513 validated for use in IC, IH & WB.
Research Category
Neuroscience
Neuroscience
Research Sub Category
Neuronal & Glial Markers
Neurochemistry & Neurotrophins
Neuronal & Glial Markers
Neurochemistry & Neurotrophins
Western Blot:
20 μg/mL of a previous lot was used on western blot under non-reducing conditions only.{See Ellezam, 2003}
Immunocytochemistry:
5-10 µg/mL of a previous lot was used, methanol fixation required.
Optimal working dilutions must be determined by end user.
20 μg/mL of a previous lot was used on western blot under non-reducing conditions only.{See Ellezam, 2003}
Immunocytochemistry:
5-10 µg/mL of a previous lot was used, methanol fixation required.
Optimal working dilutions must be determined by end user.
Jakość
Evaluated by immunohistochemistry on rat hippocampus.
Immunohistochemistry(paraffin):
Representative image from a previous lot.
Mouse anti-Myelin Associated Glycoprotein [MAG] (Catalog Number MAB1567) localization of MAG in rat hippocampus. Photo courtesy of Dr. Robert Sloviter, University of Arizona.
Immunohistochemistry(paraffin):
Representative image from a previous lot.
Mouse anti-Myelin Associated Glycoprotein [MAG] (Catalog Number MAB1567) localization of MAG in rat hippocampus. Photo courtesy of Dr. Robert Sloviter, University of Arizona.
Opis wartości docelowych
100 kDa
Postać fizyczna
Format: Purified
Protein A purified
Purified mouse monoclonal IgG1 in buffer containing 10 mM potassium phosphate buffer, 50 mM NaCl, pH 7.5. Contains no preservative.
Przechowywanie i stabilność
Stable for 1 year at -20ºC from date of receipt.
Komentarz do analizy
Control
Rat hippocampus tissue, rat brain lysate, PC12 cells.
Rat hippocampus tissue, rat brain lysate, PC12 cells.
Inne uwagi
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Informacje prawne
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Oświadczenie o zrzeczeniu się odpowiedzialności
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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polecane
Kod klasy składowania
10 - Combustible liquids
Klasa zagrożenia wodnego (WGK)
WGK 2
Certyfikaty analizy (CoA)
Poszukaj Certyfikaty analizy (CoA), wpisując numer partii/serii produktów. Numery serii i partii można znaleźć na etykiecie produktu po słowach „seria” lub „partia”.
Masz już ten produkt?
Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.
Infection of stationary human brain aggregates with HIV-1 SF162 and IIIB results in transient neuronal damage and neurotoxicity.
Trillo-Pazos, G, et al.
Neuropathology and Applied Neurobiology, 30, 136-147 (2004)
Myelin-associated glycoprotein reduces axonal branching and enhances functional recovery after sciatic nerve transection in rats.
Koichi Tomita,Tateki Kubo,Ken Matsuda,Kenji Yano,Masaya Tohyama,Ko Hosokawa
Glia null
Connexin29 expression, immunocytochemistry and freeze-fracture replica immunogold labelling (FRIL) in sciatic nerve.
Xinbo Li, B D Lynn, C Olson, C Meier, K G V Davidson, T Yasumura, J E Rash, J I Nagy
The European Journal of Neuroscience null
Myelin-associated glycoprotein interacts with ganglioside GT1b. A mechanism for neurite outgrowth inhibition.
Vinson, M; Strijbos, PJ; Rowles, A; Facci, L; Moore, SE; Simmons, DL; Walsh, FS
The Journal of Biological Chemistry null
A Görlich et al.
Neuroscience, 168(2), 564-572 (2010-04-17)
One strategy in localizing a sound source in the azimuthal plane is the comparison of arrival times of sound stimuli at the two ears. The processing of interaural time differences (ITDs) in the auditory brainstem was suggested by the Jeffress
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