Przejdź do zawartości
Merck
Wszystkie zdjęcia(4)

Kluczowe dokumenty

Wyświetl całą dokumentację

HCCBP1MAG-58K

Millipore

MILLIPLEX® Human Circulating Cancer Biomarker Magnetic Bead Panel - Cancer Multiplex Assay

Circulating Cancer Biomarker Bead-Based Multiplex Assays using the Luminex technology enables the simultaneous analysis of multiple oncology biomarkers in various tumor types in human serum, plasma and cell culture samples.

Synonim(y):

Millipore zestaw multipleksowy ludzkich krążących biomarkerów nowotworowych, luminex test multipleksowy ludzkich krążących biomarkerów nowotworowych, panel immunologiczny biomarkerów nowotworów ludzkich

Zaloguj sięWyświetlanie cen organizacyjnych i kontraktowych
Wszystkie zdjęcia(4)

About This Item

Kod UNSPSC:
12161503
eCl@ss:
32161000
NACRES:
NA.84

Poziom jakości

200

reaktywność gatunkowa

human

producent / nazwa handlowa

Milliplex®

assay range

accuracy: 35-108%
standard curve range: 0.09-67 mU/mL
(β-HCG)
standard curve range: 0.7-500 pg/mL
(IL-6)
standard curve range: 1.3-1000 pg/mL
(IL-8, TNFα)
standard curve range: 2.7-2000 pg/mL
(TRAIL, TGF-α)
standard curve range: 6.9-5000 pg/mL
(SCF)

metody

multiplexing: suitable

metoda wykrywania

fluorometric (Luminex xMAP)

Warunki transportu

wet ice

Powiązane kategorie

Opis ogólny

Circulating cancer biomarkers give insight beyond intracellular oncogenesis and into how the body responds to the presence of a tumor, the dysregulation of homeostasis, and the relationship between a tumor and its environment. Multianalyte panels have become essential tools that enable researchers to measure cancer biomarkers simultaneously, teasing out these relationships and applying them to understand tumor biology.

MILLIPLEX® Circulating Cancer Biomarker Panel 1 is a 25-plex kit that can be used for the simultaneous quantification of any or all of the following analytes in serum, plasma and tissue/cell lysate and culture supernatant samples: AFP, CA125, CA15-3, CA19-9, CEA, CYFRA21-1, sFas, sFasL, FGF2, β-HCG, HE4, HGF, IL-6, IL-8, Leptin, MIF, Osteopontin, Prolactin, PSA (free), PSA (total), SCF, TGFα, TNFα, TRAIL and VEGF. Note that certain biomarkers are tumor specific, such as PSA, while others, such as IL-8, have been detected in many cancers. PSA (free) and PSA (total) cannot be plexed together. This kit uses a 96-well format, contains a lyophilized standard cocktail, two internal assay quality controls and can measure up to 38 samples in duplicate.

The Luminex® xMAP® platform uses a magnetic bead immunoassay format for ideal speed and sensitivity to quantitate multiple analytes simultaneously, dramatically improving productivity while conserving valuable sample volume.

Panel Type: Circulating Cancer

Specyficzność

Cross Reactivty
Cross-reactivity between the antibodies and any of the other analytes in this panel is non-detectable or negligible.

Zastosowanie

  • Analytes: α-Fetoprotein (AFP), CA125, CA15-3, CA19-9, CEA, CYFRA21-1, sFas (TNFRSF6), sFasL, FGF-2 (FGF-basic), β-HCG (HCGβ), HE4, HGF, IL-6, IL-8 (CXCL8), Leptin, MIF, Osteopontin (OPN), Prolactin, PSA (free)*, PSA (total)*, SCF, TGFα, TNFα, TRAIL (TNFSF10), VEGF.
  • Note: Total PSA and Free PSA cannot be plexed together
  • Recommended Sample Type: Human serum, plasma or tissue/cell culture supernatants or lysates
  • Recommended Sample Dilution: 25 μL per well of 1:6 diluted plasma or serum, or 25 μL cell culture psaesaa sample undiluted or diluted in appropriate control medium
  • Assay Run Time: Overnight (16-18 hr) at 2-8°C
  • Research Category: Cancer

Cechy i korzyści

Design your multiplex kit by choosing available analytes within this panel.

Opakowanie

Everything you need in a single kit.

Komponenty

Human Circulating Cancer Biomarker Panel 1 Standard (HCC-8058)

Human Circulating Cancer Biomarker Panel 1 Quality Controls 1 and 2 (HCC-6058)

Serum Matrix (HCP-SM)
Note: Contains 0.08% Sodium Azide

Set of one 96-Well Plate with 2 Sealers (MAG-PLATE)

Assay Buffer (L-AB)
Note: Contains 0.08% Sodium Azide

10X Wash Buffer (L-WB)
Note: Contains 0.05% Proclin

Human Circulating Cancer Biomarker Panel 1 Detection Antibodies (HCC-1058 or HCC-1058-2)

Streptavidin-Phycoerythrin (L-SAPE 4)

Bead Diluent (LBD-4)

Przechowywanie i stabilność

Recommended storage for kit components is 2 - 8°C.

Inne uwagi

Please note: Total PSA and Free PSA cannot be plexed together.
Sensitivity: Refer to kit protocol for sensitivities of individual biomarkers.

Informacje prawne

Luminex is a registered trademark of Luminex Corp
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp

Oświadczenie o zrzeczeniu się odpowiedzialności

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Ta strona może zawierać tekst przetłumaczony maszynowo.

Hasło ostrzegawcze

Danger

Zwroty wskazujące rodzaj zagrożenia

H302 + H312 + H332,H317,H318,H373,H411

Klasyfikacja zagrożeń

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Sens. 1 - STOT RE 2

Organy docelowe

Respiratory Tract

Kod klasy składowania

10 - Combustible liquids

Certyfikaty analizy (CoA)

Poszukaj Certyfikaty analizy (CoA), wpisując numer partii/serii produktów. Numery serii i partii można znaleźć na etykiecie produktu po słowach „seria” lub „partia”.

Masz już ten produkt?

Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.

Odwiedź Bibliotekę dokumentów

Chen-Tzu Chiu et al.
Cancers, 12(6) (2020-06-18)
Head and neck cancer (HNC) accounts for more than 330,000 cancer deaths annually worldwide. Despite late diagnosis being a major factor contributing to HNC mortality, no satisfactory biomarkers exist for early disease detection. Cytoplasmic gelsolin (cGSN) was discovered to predict
A combined blood based gene expression and plasma protein abundance signature for diagnosis of epithelial ovarian cancer--a study of the OVCAD consortium.
Pils, D; Tong, D; Hager, G; Obermayr, E; Aust, S; Heinze, G; Kohl, M; Schuster, E; Wolf et al.
BMC Cancer null
Sandra Tuyaerts et al.
Frontiers in nutrition, 5, 138-138 (2019-01-29)
Curcumin is a botanical with anti-tumor and immunomodulatory properties. We hypothesized that curcumin supplementation might influence inflammatory biomarker levels in endometrial carcinoma (EC). In this open-label, non-randomized phase 2 study (NCT02017353), seven EC patients consumed 2 g/day Curcumin Phytosome (CP)
Jonathan A Kluge et al.
Proceedings of the National Academy of Sciences of the United States of America, 113(21), 5892-5897 (2016-05-11)
Advanced personalized medical diagnostics depend on the availability of high-quality biological samples. These are typically biofluids, such as blood, saliva, or urine; and their collection and storage is critical to obtain reliable results. Without proper temperature regulation, protein biomarkers in
Effect of different exercise modalities plus a hypocaloric diet on inflammation markers in overweight patients: a randomised trial.
Loria-Kohen, V; Fernandez-Fernandez, C; Bermejo, LM; Morencos, E; Romero-Moraleda et al.
Clinical Nutrition (Edinburgh, Scotland) null
Wyświetl wszystkie powiązane dokumenty

Powiązane treści

Multiplex Cancer Assays for Cancer Biomarker Detection | MILLIPLEX® Assays

Detection of cancer biomarkers through multiplex cancer assays can accelerate studies of normal homeostasis and tumorigenic processes. See how MILLIPLEX® multiplex cancer assays are advancing various cancer research areas including lung cancer, breast cancer, and immuno-oncology research.

Testy multipleksowe do wykrywania biomarkerów nowotworowych | Testy MILLIPLEX®

Wykrywanie biomarkerów nowotworowych za pomocą multipleksowych testów nowotworowych może przyspieszyć badania normalnej homeostazy i procesów nowotworowych. Zobacz, jak multipleksowe testy nowotworowe MILLIPLEX® rozwijają różne obszary badań nad rakiem, w tym raka płuc, raka piersi i badania immunoonkologiczne.

Multiplexing Cancer & Metastasis Signaling Pathways | MILLIPLEX® Assays

Learn how multiplexing with MILLIPLEX® multiplex assays can help simplify cancer research by measuring multiple circulating biomarkers at once. Find multiplex panels to analyze JAK-STAT, mTOR, MAPK, SAPK, TGFβ signaling pathways, and more.

Nasz zespół naukowców ma doświadczenie we wszystkich obszarach badań, w tym w naukach przyrodniczych, materiałoznawstwie, syntezie chemicznej, chromatografii, analityce i wielu innych dziedzinach.

Skontaktuj się z zespołem ds. pomocy technicznej