GF338
IL-6,
Human Recombinant Animal Free
Synonim(y):
Interleukin-6, IL6
Zaloguj sięWyświetlanie cen organizacyjnych i kontraktowych
About This Item
Polecane produkty
Opis ogólny
IL-6 is a pleiotropic cytokine that plays an important role in host defense by regulating immune and inflammatory responses. Produced by T cells, monocytes, fibroblasts, endothelial cells and keratinocytes, IL-6 has diverse biological functions. It stimulates B-cell differentiation and antibody production, synergizes with IL-3 in megakaryocyte development and platelet production, induces expression of hepatic acute-phase proteins, and regulates bone metabolism. IL-6 signals through
the IL-6 receptor system that consists of two chains, IL-6R and gp130. Murine IL-6 is inactive on human cells, while both
human and murine are equally active on murine cells.
Recombinant human IL-6 is a 20.9 kDa protein containing 184 amino acid residues.
the IL-6 receptor system that consists of two chains, IL-6R and gp130. Murine IL-6 is inactive on human cells, while both
human and murine are equally active on murine cells.
Recombinant human IL-6 is a 20.9 kDa protein containing 184 amino acid residues.
Product Source: Protein is expressed in E.coli.
The protein is manufactured without the use of any animal products/reagents and is considered Animal-Free and can be used in protocols where possible transmisson of animal viruses and contamination must be avoided.
The protein is manufactured without the use of any animal products/reagents and is considered Animal-Free and can be used in protocols where possible transmisson of animal viruses and contamination must be avoided.
Zastosowanie
Research Category
Stem Cell Research
Stem Cell Research
Research Sub Category
Growth Factors & Receptors
Growth Factors & Receptors
Jakość
Determined by its ability to stimulate the proliferation of mouse B9 cells.
Postać fizyczna
Product is presented in 10mM Sodium Phosphate, pH 7.5 and is filtered through a 0.2 micron filter before lyophilization.
Przechowywanie i stabilność
Store at -20°C for up to 4 months from date of receipt Centrifuge the vial prior to opening.
Reconstitute in water to a concentration of 0.1-0.5 mg/ml. Do not vortex. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein and store in working aliquots at -20°C.
Reconstitute in water to a concentration of 0.1-0.5 mg/ml. Do not vortex. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein and store in working aliquots at -20°C.
Oświadczenie o zrzeczeniu się odpowiedzialności
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Kod klasy składowania
11 - Combustible Solids
Klasa zagrożenia wodnego (WGK)
WGK 1
Certyfikaty analizy (CoA)
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