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ABN2300C3

Sigma-Aldrich

Neuro-Chrom Pan Neuronal Marker Antibody-Rabbit, Cy3 Conjugate

Neuro-Chrom, from rabbit

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About This Item

Kod UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41

pochodzenie biologiczne

rabbit

Poziom jakości

białko sprzężone

CY3 conjugate

klon

polyclonal

reaktywność gatunkowa

mouse, rat

producent / nazwa handlowa

Neuro-Chrom

metody

immunocytochemistry: suitable
immunofluorescence: suitable
immunohistochemistry: suitable

Warunki transportu

wet ice

docelowa modyfikacja potranslacyjna

unmodified

Opis ogólny

Antibodies to neuronal proteins have become critical tools for identifying neurons and discerning morphological characteristics in culture and complex tissue. While the labeling from classic histological techniques such as Golgi staining and modern molecular approaches such as GFP constructs yield excellent cytoarchitectural detail, these approaches are technically challenging and impractical for many neuroscience research needs. Neuron-specific antibodies are convenient precision tools useful in revealing cytoarchitecture, but are limited to the protein target distribution within the neuron, which may differ greatly from nucleus to soma to dendrite and axon. To achieve as complete a morphological staining as possible across all parts of neurons, Millipore has developed a polyclonal antibody blend that reacts against key somatic, nuclear, dendritic, and axonal proteins distributed across the pan-neuronal architecture that can then be detected by a single secondary antibody. This antibody cocktail has been validated in diverse methods, cell culture and immuno-histochemistry, giving researchers a convenient and specific qualitative and quantitative tool for studying neuronal morphology.

Specyficzność

Cat. # ABN2300C is specific to axons (neurites), dendrites, nucleus, and the cell body of neurons.
Reactivity with other species has not been determined.

Immunogen

Epitope: Whole Neuron Marker

Zastosowanie

Neuro-Chrom Pan Neuronal Marker-Rabbit, Cy3 Conjugate is an antibody targeting the Pan Neuronal Marker protein, validated for use in ICC, IHC & IF.
Research Category
Neuroscience
Research Sub Category
Neuronal & Glial Markers

Jakość

Routinely tested Rat E18 cortex primary neurons in Immunocytochemistry.

Postać fizyczna

Polyclonal antibody cocktail blend conjugated to Cy3 in PBS buffer with 15mg/mL BSA and 0.05% NaN3

Przechowywanie i stabilność

Maintain at 2-8°C for up to 1 year from date of receipt.

Komentarz do analizy

Control
Rat E18 cortex primary neuron cell culture or mouse adult brain cryosections.

Oświadczenie o zrzeczeniu się odpowiedzialności

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Kod klasy składowania

12 - Non Combustible Liquids

Klasa zagrożenia wodnego (WGK)

WGK 2

Temperatura zapłonu (°F)

Not applicable

Temperatura zapłonu (°C)

Not applicable


Certyfikaty analizy (CoA)

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Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.

Odwiedź Bibliotekę dokumentów

Zoeb Jiwaji et al.
Nature communications, 13(1), 135-135 (2022-01-12)
Alzheimer's disease (AD) alters astrocytes, but the effect of Aß and Tau pathology is poorly understood. TRAP-seq translatome analysis of astrocytes in APP/PS1 ß-amyloidopathy and MAPTP301S tauopathy mice revealed that only Aß influenced expression of AD risk genes, but both

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