ABE409

Anti-UTX Antibody

from rabbit, purified by affinity chromatography

• Synonim(y): Lysine-specific demethylase 6A, Histone demethylase UTX, Ubiquitously-transcribed TPR protein on the X chromosome, Ubiquitously-transcribed X chromosome tetratricopeptide repeat protein
• Kod UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Właściwości

• pochodzenie biologiczne: rabbit
• Poziom jakości: 100
• forma przeciwciała: affinity isolated antibody
• rodzaj przeciwciała: primary antibodies
• klon: polyclonal
• oczyszczone przez: affinity chromatography
• reaktywność gatunkowa: human, mouse
• reaktywność gatunkowa (przewidywana na podstawie homologii): chimpanzee (based on 100% sequence homology)
• metody: immunocytochemistry: suitable; western blot: suitable
• numer dostępu NCBI: NP_066963
• numer dostępu UniProt: O15550
• Warunki transportu: wet ice
• docelowa modyfikacja potranslacyjna: unmodified
• informacje o genach: human ... KDM6A(7403)

Opis

Opis ogólny

Histone demethylase UTX is also known as Lysine-specific demethylase 6A, Ubiquitously-transcribed TPR protein on the X chromosome, and Ubiquitously-transcribed X chromosome tetratricopeptide repeat protein. UTX is a histone demethylase that specifically demethylates trimethylated and dimethylated but not monomethylated histone H3 ′Lys-27′. UTX is involved in regulation of posterior development, and defects can cause Kabuki syndrome type 2 (KABUK2)

Specyficzność

Other homologies: Canine (99% sequence homology) and Bovine (96% sequence homology).

Immunogen

GST-tagged recombinant protein corresponding to human UTX.

Zastosowanie

Detect Histone demethylase UTX using this rabbit polyclonal antibody, Anti-UTX Antibody validated for use in western blotting & ICC.

Immunocytochemistry Analysis: A 1:50 dilution from a representative lot detected UTX in HeLa, A431, and 3T3 cells.

Research Category
Epigenetics & Nuclear Function

Research Sub Category
Chromatin Biology

Jakość

Evaluated by Western Blotting in HeLa nuclear extract.

Western Blotting Analysis: 0.5 µg/mL of this antibody detected UTX in 10 µg of HeLa nuclear extract.

Opis wartości docelowych

~154 kDa observed. Uncharacterized band(s) may appear in some lysates.

Postać fizyczna

Antigen Affinity Purified

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Przechowywanie i stabilność

Stable for 1 year at 2-8°C from date of receipt.

Komentarz do analizy

Control
HeLa nuclear extract

Inne uwagi

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Oświadczenie o zrzeczeniu się odpowiedzialności

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 12 - Non Combustible Liquids
• Klasa zagrożenia wodnego (WGK): WGK 1
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable