AB6019

Anti-Thymosin beta-4 Antibody

from rabbit, purified by affinity chromatography

• Synonim(y): thymosin beta 4, X-linked, prothymosin beta-4, thymosin, beta 4, thymosin, beta 4, X chromosome, T beta-4
• Kod UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Właściwości

• pochodzenie biologiczne: rabbit
• Poziom jakości: 100
• forma przeciwciała: affinity isolated antibody
• rodzaj przeciwciała: primary antibodies
• klon: polyclonal
• oczyszczone przez: affinity chromatography
• reaktywność gatunkowa: mouse, human
• reaktywność gatunkowa (przewidywana na podstawie homologii): rat (based on 100% sequence homology)
• metody: immunocytochemistry: suitable; western blot: suitable
• numer dostępu NCBI: NP_066932
• numer dostępu UniProt: P62328
• Warunki transportu: wet ice
• docelowa modyfikacja potranslacyjna: unmodified
• informacje o genach: human ... TMSB4X(7114)

Opis

Opis ogólny

Thymosin beta-4 is the most prevalent of the cytoplasmic G-actin binding proteins belonging to the highly conserved thymosin beta family. Known to bind actin monomers, Thymosin beta-4 sequesters G-actin in a manner that prevents actin polymerization. Thymosin beta-4 plays several important roles including induction of tissue remodeling, wound healing in both cell and tissue injuries, and cell differentiation via mechanisms that have yet to be fully elucidated. It is involved in the regulation of the cytoskeleton, and thereby influences an array of cellular processes. Within the brain, Thymosin beta-4 is associated with the neurite extension and migration of neurons. Expression has been observed in various hemopoietic and lymphoid malignant cell lines.

Specyficzność

Th antibody recognizes the internal domain of Thymosin beta-4.

Immunogen

GST-tagged recombinant protein corresponding to the internal domain of human Thymosin beta-4.

Zastosowanie

Anti-Thymosin beta-4 Antibody is an antibody against Thymosin beta-4 for use in WB & IC.

Western Blot (Snap i.d.) Analysis: 1 µg/mL from a previous lot detected Thymosin beta-4 on 10 µg of recombinant Thymosin beta-4.

Immunocytochemistry Analysis: 1:500 dilution from a previous lot detected Thymosin beta-4 in NIH/3T3, HeLa, and A431 cells.

Jakość

Evaluated by Western Blot in recombinant Thymosin beta-4.

Western Blot Analysis: 1 µg/mL of the antibody detected Thymosin beta-4 on 10 µg of recombinant Thymosin beta-4.

Opis wartości docelowych

~ 33kDa observed

Komentarz do analizy

Control
Recombinant Thymosin beta-4

Inne uwagi

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

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Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 12 - Non Combustible Liquids
• Klasa zagrożenia wodnego (WGK): WGK 1
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable