AB3383-I

Anti-UTF1 Antibody

from rabbit, purified by affinity chromatography

• Synonim(y): UTF1, Undifferentiated embryonic cell transcription factor 1
• Kod UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Właściwości

• pochodzenie biologiczne: rabbit
• Poziom jakości: 100
• forma przeciwciała: affinity isolated antibody
• rodzaj przeciwciała: primary antibodies
• klon: polyclonal
• oczyszczone przez: affinity chromatography
• reaktywność gatunkowa: rat, mouse
• reaktywność gatunkowa (przewidywana na podstawie homologii): human (based on 100% sequence homology)
• metody: immunohistochemistry: suitable; western blot: suitable
• numer dostępu NCBI: NP_003568
• numer dostępu UniProt: Q5T230
• Warunki transportu: wet ice
• docelowa modyfikacja potranslacyjna: unmodified
• informacje o genach: human ... UTF1(8433)

Opis

Opis ogólny

Undifferentiated embryonic cell transcription factor 1 is a nucleus protein encoded by the UTF1 gene in human and functions as a transcriptional coactivator of ATF2. UTF1 is reported to interact with the ATF-2 metal binding motif via the leucine zipper motif within its conserved domain 2 (CD2) and both CD1 & CD2 of UTF1 and also independently mediates association with TATA-binding protein-containing complex. (PMID 9749258)

Specyficzność

Other homologies: mouse, rat 95%.

Immunogen

Epitope: Near N-terminus

KLH-conjugated linear peptide corresponding to human UTF1 near N-terminus.

Zastosowanie

Anti-UTF1 Antibody is an antibody against UTF1 for use in Western Blotting and Immunohistochemistry.

Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected UTF1 in mouse kidney and rat liver tissue.

Research Category
Epigenetics & Nuclear Function

Research Sub Category
Nuclear Receptors

Jakość

Evaluated by Western Blotting in mouse embryonic stem cell lysate.

Western Blotting Analysis: 0.5 µg/mL of this antibody detected UTF1 in 10 µg of mouse embryonic stem cell lysate.

Opis wartości docelowych

~48 kDa observed. UTF1, a novel transcriptional coactivator expressed in pluripotent embryonic stem cells and extra-embryonic cells (Okuda, A., et al. (1998). EMBO. 17(7):2019–2032).

Powiązanie

Replaces: AB3383

Postać fizyczna

Affinity

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Przechowywanie i stabilność

Stable for 1 year at 2-8°C from date of receipt.

Inne uwagi

Concentration: Please refer to lot specific datasheet.

Oświadczenie o zrzeczeniu się odpowiedzialności

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 12 - Non Combustible Liquids
• Klasa zagrożenia wodnego (WGK): WGK 1
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable