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Key Documents

AB1834P

Sigma-Aldrich

Anti-Monocyte Chemotactic Protein-1 Antibody

Chemicon®, from rabbit

Synonim(y):

MCP-1, MCAF, CCL2

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About This Item

Kod UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41

pochodzenie biologiczne

rabbit

Poziom jakości

forma przeciwciała

affinity purified immunoglobulin

rodzaj przeciwciała

primary antibodies

klon

polyclonal

oczyszczone przez

affinity chromatography

reaktywność gatunkowa

rat

producent / nazwa handlowa

Chemicon®

metody

ELISA: suitable
neutralization: suitable
western blot: suitable

numer dostępu NCBI

numer dostępu UniProt

Warunki transportu

wet ice

docelowa modyfikacja potranslacyjna

unmodified

informacje o genach

human ... CCL2(6347)

Specyficzność

Reacts with rat MCP-1

Immunogen

Highly pure (>98%) recombinant rat MCP-1

Zastosowanie

Anti-Monocyte Chemotactic Protein-1 Antibody is an antibody against Monocyte Chemotactic Protein-1 for use in ELISA, WB, NEUT.
ELISA: To detect rat MCP-1 (MCAF) by direct ELISA (using 100 μL/well antibody solution) a concentration of at lease 0.5 μg/mL of this antibody is required. Should allow detection of 0.2 - 0.4 ng/well of recombinant rat MCP-1 (MCAF).

Western blot: 0.1 - 0.2 μg/mL, this dilution should offer a detection limit of 1.5-3.0 ng/lane, under either reducing or non-reducing conditions.

Neutralization: To yield one-half maximal inhibition [ND50] of the biological activity of rat MCP-1 (100 ng/mL), a concentration of 4.0-6.0 μg/mL of this antibody is required.

Optimal working dilutions must be determined by the end user.
Research Category
Inflammation & Immunology
Research Sub Category
Cytokines & Cytokine Receptors

Postać fizyczna

Affinity purified immunoglobulin. Lyophilized from 0.5X PBS pH 7.4. Contains no preservative. Reconstitute with sterile distilled water to 0.1 - 1.0 mg/ml.

Przechowywanie i stabilność

Maintain lyophilized material desiccated at 2°-8&deg:C for up to 12 months from date of receipt. After reconstitution maintain at -20°C in convenient undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles.

Inne uwagi

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Informacje prawne

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Oświadczenie o zrzeczeniu się odpowiedzialności

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Kod klasy składowania

13 - Non Combustible Solids

Klasa zagrożenia wodnego (WGK)

WGK 3

Temperatura zapłonu (°F)

Not applicable

Temperatura zapłonu (°C)

Not applicable


Certyfikaty analizy (CoA)

Poszukaj Certyfikaty analizy (CoA), wpisując numer partii/serii produktów. Numery serii i partii można znaleźć na etykiecie produktu po słowach „seria” lub „partia”.

Masz już ten produkt?

Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.

Odwiedź Bibliotekę dokumentów

Fibrogenesis in pediatric cholestatic liver disease: role of taurocholate and hepatocyte-derived monocyte chemotaxis protein-1 in hepatic stellate cell recruitment.
Grant A Ramm, Ross W Shepherd, Anita C Hoskins, Sonia A Greco, Agnieszka D Ney et al.
Hepatology null
Regulated expression of matrix metalloproteinases, inflammatory mediators, and endometrial matrix remodeling by 17beta-estradiol in the immature rat uterus.
Russo, LA; Peano, BJ; Trivedi, SP; Cavalcanto, TD; Olenchock, BA; Caruso, JA; Smolock et al.
Reproductive Biology and Endocrinology null
Clémence Guiraut et al.
International journal of molecular sciences, 17(12) (2016-11-30)
The medium-size intra-cranial arteries arising from the carotid bifurcation are prone to perinatal arterial ischemic strokes (PAIS). PAIS' physiopathology needs to be better understood to develop preventive and therapeutic interventions that are currently missing. We hypothesized that materno-fetal inflammation leads
Marie-Elsa Brochu et al.
Journal of neuroinflammation, 8, 55-55 (2011-05-24)
Preterm and term newborns are at high risk of brain damage as well as subsequent cerebral palsy and learning disabilities. Indeed, hypoxia-ischemia (HI), pathogen exposures, and associated intracerebral increase of pro-inflammatory cytokines have all been linked to perinatal brain damage.
Defining the ATM-mediated barrier to tumorigenesis in somatic mammary cells following ErbB2 activation.
Reddy JP, Peddibhotla S, Bu W, Zhao J, Haricharan S, Du YC, Podsypanina K, Rosen JM et al.
Proceedings of the National Academy of Sciences of the USA null

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