AB10140
Anti-Drebrin A/E Antibody
from rabbit, purified by affinity chromatography
Synonim(y):
Developmentally-regulated brain protein, drebrin 1, drebrin E, drebrin E2
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About This Item
Kod UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Polecane produkty
pochodzenie biologiczne
rabbit
Poziom jakości
forma przeciwciała
affinity isolated antibody
rodzaj przeciwciała
primary antibodies
klon
polyclonal
oczyszczone przez
affinity chromatography
reaktywność gatunkowa
rat, human, mouse
metody
immunocytochemistry: suitable
western blot: suitable
numer dostępu NCBI
numer dostępu UniProt
Warunki transportu
wet ice
docelowa modyfikacja potranslacyjna
unmodified
informacje o genach
human ... DBN1(1627)
Opis ogólny
The developmentally-regulated neuron-specific protein, Drebrin A, is expressed first at the time of outgrowth and maturation of dendrites, and is localized within dendrites of the adult brain. Drebrin E+A- signals have been observed in the cell bodies of migrating neuroblasts in the core region; however, only fibrous and punctate drebrin E+A- signals were observed in postmigratory neuroblasts at the outer layers. Studies have demonstrated that the disappearance of drebrin E+A- signals from the cell body coincides with the cessation of neuronal migration. The disappearance of drebrin E from the cell body may be a molecular switch for the cessation of migration in newly generated neuroblast
Specyficzność
Cat. # AB10140 detects the internal domain of Drebrin A/E.
May react with human based on sequence homology. Reactivity with other species has not been determined.
Immunogen
Epitope: Internal Domain
KLH conjugated synthetic linear peptide.
Zastosowanie
Detect Drebrin A/E using this Anti-Drebrin A/E Antibody validated for use in WB & IC.
Immunocytochemistry: Proven to react with Drebrin A/E in 16 DIV rat cortical neurons. Photo courtesy of Dr. Gang Lui, Drexel University.
Research Category
Neuroscience
Neuroscience
Research Sub Category
Synapse & Synaptic Biology
Synapse & Synaptic Biology
Jakość
Western Blot:
A 1:5,000 dilution of this antibody was used to detect embryonic rat brain (day 16) tissue lysate.
A 1:5,000 dilution of this antibody was used to detect embryonic rat brain (day 16) tissue lysate.
Opis wartości docelowych
~77 kDa
Postać fizyczna
Antigen Affinity Purified
Purified rabbit polyclonal antibody in PBS with 0.05% NaN3.
Przechowywanie i stabilność
Stable for 1 year at 2-8ºC from date of receipt.
Komentarz do analizy
Control
Embryonic rat brain (day 16) tissue lysate.
Embryonic rat brain (day 16) tissue lysate.
Inne uwagi
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Oświadczenie o zrzeczeniu się odpowiedzialności
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Kod klasy składowania
10 - Combustible liquids
Klasa zagrożenia wodnego (WGK)
WGK 2
Temperatura zapłonu (°F)
Not applicable
Temperatura zapłonu (°C)
Not applicable
Certyfikaty analizy (CoA)
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Cell death & disease, 5, e1268-e1268 (2014-05-31)
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