565950

Sialyl Lewis x, Sodium Salt

Enzymatically prepared tetrasaccharide which acts as a minimal binding ligand for E-selectins.

• Synonim(y): Sialyl Lewis x, Sodium Salt, SLe ^x, Neu5Acα2,3Galβ1,4(Fucα1,3)GlcNAc, SLe^x, Neu5Acα2,3Galβ1,4(Fucα1,3)GlcNAc
• Wzór empiryczny (zapis Hilla): C₃₁H₅₁N₂NaO₂₃
• Numer CAS: 98603-84-0
• Masa cząsteczkowa: 842.73
• Numer MDL: MFCD00270073
• Kod UNSPSC: 12352201
• NACRES: NA.79

Właściwości

• Poziom jakości: 100
• Próba: ≥95% (TLC)
• Postać: solid
• producent / nazwa handlowa: Calbiochem^®
• warunki przechowywania: OK to freeze
• kolor: white
• rozpuszczalność: water: 2 mg/mL
• Warunki transportu: wet ice
• temp. przechowywania: −20°C
• InChI: 1S/C31H52N2O23/c1-9-18(43)21(46)22(47)28(51-9)53-24(12(5-34)32-10(2)38)25(15(42)7-36)54-29-23(48)27(20(45)16(8-37)52-29)56-31(30(49)50)4-13(40)17(33-11(3)39)26(55-31)19(44)14(41)6-35/h5,9,12-29,35-37,40-48H,4,6-8H2,1-3H3,(H,32,38)(H,33,39)(H,49,50)/t9-,12-,13-,14+,15+,16+,17+,18+,19+,20-,21+,22-,23+,24+,25+,26+,27-,28-,29-,31-/m0/s1
• Klucz InChI: LAQPKDLYOBZWBT-NYLDSJSYSA-N

Opis

Opis ogólny

Enzymatically prepared tetrasaccharide which acts as a minimal binding ligand for E-selectins. SLe^x reduces injury following ischemia and reperfusion and immune complex-induced acute lung injury in animal models. In both of these models, SLe^x is presumed to act by blocking E-selectin-mediated neutrophil recruitment to sites of inflammation.

Enzymatically prepared tetrasaccharide which acts as a minimal binding ligand for E-selectins. SLe^x reduces injury following ischemia, reperfusion and immune complex-induced acute lung injury in animal models. In both of these models, SLe^x is presumed to act by blocking E-selectin-mediated neutrophil recruitment to sites of inflammation.

Ostrzeżenie

Toxicity: Standard Handling (A)

Inne uwagi

Seekamp, A., et al. 1994. Am. J. Pathol.144, 592.
Mulligan, M.S., et al. 1993. J. Exp. Med.178, 623.
Ichikawa, Y., et al. 1992. J. Am. Chem. Soc. 114, 9283.
Lasky, L.A. 1992. Science 258, 964.

Informacje prawne

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

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Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 11 - Combustible Solids
• Klasa zagrożenia wodnego (WGK): WGK 3
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable