537011
Prolyl Endopeptidase Inhibitor II
The Prolyl Endopeptidase Inhibitor II, also referenced under CAS 108708-25-4, controls the biological activity of Prolyl Endopeptidase. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
Synonim(y):
Prolyl Endopeptidase Inhibitor II, Z-PP-CHO
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About This Item
Wzór empiryczny (zapis Hilla):
C18H22N2O4
Numer CAS:
Masa cząsteczkowa:
330.38
Kod UNSPSC:
12352200
Polecane produkty
Poziom jakości
Próba
≥97% (HPLC)
Postać
oil
producent / nazwa handlowa
Calbiochem®
warunki przechowywania
OK to freeze
protect from light
kolor
colorless to off-white
rozpuszczalność
DMSO: 10 mg/mL
DMF: soluble
ethyl acetate: soluble
Warunki transportu
ambient
temp. przechowywania
−20°C
Opis ogólny
A cell-permeable dipeptide aldehyde that acts as a specific, potent, slow and tight-binding transition state analog inhibitor of prolyl endopeptidase (Ki = 350 pM and 500 pM for mouse brain and human brain prolyl endopeptidase, respectively). Reported to form a hemiacetal with the active-site serine.
A cell-permeable dipeptide aldehyde that acts as a specific, potent, slow, and tight-binding transition state analog inhibitor of prolyl endopeptidase (Ki = 350 pM and 500 pM for mouse brain and human brain, respectively). Reported to form a hemiacetal with the active site serine of the enzyme.
Działania biochem./fizjol.
Cell permeable: yes
Primary Target
Mouse brain prolylendooeotidase
Mouse brain prolylendooeotidase
Product does not compete with ATP.
Reversible: no
Target Ki: 350 pM and 500 pM for mouse brain and human brain prolyl endopeptidase, respectively
Opakowanie
Packaged under inert gas
Ostrzeżenie
Toxicity: Standard Handling (A)
Sekwencja
Z-Pro-Pro-CHO
Rekonstytucja
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Inne uwagi
Fülöp, V., et al. 1998. Cell94, 161.
Kahyaoglu, A., et al. 1997. Biochem. J.322, 839.
Bakker, A.V., et al. 1990. Biochem. J.271, 559.
Wilk, S., and Orlowski, M. 1983. J. Neurochem.41, 69.
Kahyaoglu, A., et al. 1997. Biochem. J.322, 839.
Bakker, A.V., et al. 1990. Biochem. J.271, 559.
Wilk, S., and Orlowski, M. 1983. J. Neurochem.41, 69.
Informacje prawne
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
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Kod klasy składowania
10 - Combustible liquids
Klasa zagrożenia wodnego (WGK)
WGK 1
Temperatura zapłonu (°F)
Not applicable
Temperatura zapłonu (°C)
Not applicable
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