528178

Plasminogen, EACA- and Lysine-Free, Human Plasma

• Synonim(y): Plasminogen, EACA- and Lysine-Free, Human Plasma, Profibrinolysin, Plasma Trypsinogen
• Numer CAS: 9001-91-6
• Numer MDL: MFCD00131922
• Kod UNSPSC: 12352202
• NACRES: NA.25

Właściwości

• Postać: lyophilized
• Poziom jakości: 100
• aktywność właściwa: 7 units/mg protein
• producent / nazwa handlowa: Calbiochem^®
• warunki przechowywania: OK to freeze
• rozpuszczalność: water: soluble
• Warunki transportu: ambient
• temp. przechowywania: −20°C

Opis

Opis ogólny

Native plasminogen (EACA- and lysine-free) from human plasma. Plasminogen is a single chain glycoprotein found in normal plasma at ~12 mg per deciliter, and is the inactive precursor of the serine protease plasmin.

Native plasminogen (EACA- and lysine-free) from human plasma. Single chain glycoprotein containing 790 amino acid residues. Found in normal plasma at about 12 mg/100 ml. Inactive precursor of the serine protease plasmin. It is converted to the active protease by cleavage at Arg⁵⁶⁰.

Ostrzeżenie

Toxicity: Irritant (B)

Definicja jednostki

One unit is defined as the amount of enzyme that will hydrolyze 1 µmol of N-tosyl-Gly-Pro-Lys-pNA per min at 25°C, pH 7.8.

Postać fizyczna

Lyophilized from 20 mM sodium phosphate buffer, 10 mg D-mannitol, 10 mg NaCl.

Uwaga dotycząca przygotowania

Prepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.

Rekonstytucja

Following reconstitution, aliquot and freeze (-20°C) for long-term storage or refrigerate (4°C) for short-term storage. Stock solutions are stable for at least 1 week at 4°C or for 1-2 months at -20°C.

Inne uwagi

Sun, Z., et al. 2002. Biochim. Biophys. Acta1596, 182.
Robbins, K.C., et al. 1967. J. Biol. Chem.242, 2333.

Informacje prawne

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

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Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 11 - Combustible Solids
• Klasa zagrożenia wodnego (WGK): WGK 3