344911

Fura-2 LR/AM

Acetoxymethyl (AM) derivative of FURA-PE3 with spectral properties similar to the parent compound.

• Synonim(y): Fura-2 LR/AM, Fura-2 Leakage Resistant (AM)
• Wzór empiryczny (zapis Hilla): C₅₅H₆₃N₅O₂₉
• Numer CAS: 172890-84-5
• Masa cząsteczkowa: 1258.10
• Numer MDL: MFCD00285848
• Kod UNSPSC: 12171500
• NACRES: NA.25

Właściwości

• Poziom jakości: 100
• Próba: ≥95% (HPLC)
• Postać: gum
• producent / nazwa handlowa: Calbiochem^®
• warunki przechowywania: OK to freeze; protect from light
• kolor: light yellow
• rozpuszczalność: DMSO: 10 mg/mL
• fluorescencja: λ_ex 368 nm (low); λ_ex 374 nm (high); λ_em 518 nm (low); λ_em 524 nm (high)
• Warunki transportu: ambient
• temp. przechowywania: −20°C
• InChI: 1S/C55H63N5O29/c1-33(61)76-27-82-49(68)22-57-11-13-58(14-12-57)48(67)10-8-39-7-9-41(59(23-50(69)83-28-77-34(2)62)24-51(70)84-29-78-35(3)63)44(17-39)74-15-16-75-45-18-40-19-46(54-56-21-47(89-54)55(73)87-32-81-38(6)66)88-43(40)20-42(45)60(25-52(71)85-30-79-36(4)64)26-53(72)86-31-80-37(5)65/h7,9,17-21H,8,10-16,22-32H2,1-6H3
• Klucz InChI: CGAZNAYDEAJZHQ-UHFFFAOYSA-N

Opis

Opis ogólny

Acetoxymethyl (AM) derivative of FURA-PE3 with spectral properties similar to the parent compound. Can be loaded into cells in a manner similar to FURA 2/AM. Hydrolysis by non-specific esterases traps the indicator in the cytosol. Compared to FURA-2, it is retained longer in the cell. Note: 1 set = 10 x 50 µg.

An acetoxymethyl (AM) derivative of FURA-PE3. with spectral properties similar to the parent compound. Can be loaded into cells in a manner similar to FURA 2/AM (Cat. No. 344905). Hydrolysis by non-specific esterases traps the indicator in the cytosol. Spectral properties in the presence of low calcium concentrations (ex. 364 nm, em. 508 nm) differ from those during high calcium conditions (ex. 335 nm, em. 495 nm). Note: 1 set = 10 x 50 µg.

Działania biochem./fizjol.

Cell permeable: no

Primary Target
Calcium Probes

Product does not compete with ATP.

Reversible: no

Ostrzeżenie

Toxicity: Standard Handling (A)

Rekonstytucja

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.

Inne uwagi

Abe, F., et al. 1995. Br. J. Pharmacol.116, 3000.
Vorndran, C., et al. 1995. Biophys. J.69, 2114.

Informacje prawne

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

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Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 11 - Combustible Solids
• Klasa zagrożenia wodnego (WGK): WGK 3
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable