341600

Fibrinogen, Fragment D, Human Plasma

Fibrinogen fragment D is a thermolabile native human plasma protein prepared by digestion of purified fibrinogen followed by preparative electrophoresis.

• Kod UNSPSC: 12352202
• NACRES: NA.41

Właściwości

• Poziom jakości: 200
• Postać: lyophilized
• producent / nazwa handlowa: Calbiochem^®
• warunki przechowywania: OK to freeze
• zanieczyszczenia: ≤1% Fragment E
• rozpuszczalność: sterile distilled water: 200 μg/mL
• Warunki transportu: ambient
• temp. przechowywania: −20°C

Opis

Opis ogólny

Native fibrinogen fragment D from human plasma prepared by plasmin digestion of purified fibrinogen followed by preparative electrophoresis. Thermolabile core fragment of fibrinogen. Complete proteolysis of a single fibrinogen molecule produces two D and one E fragments. The D and E fragments have no common antigenic determinants; therefore, no cross-reaction occurs. Reported to increase endothelial membrane permeability to albumin.

Native fibrinogen fragment D from human plasma prepared by plasmin digestion of purified fibrinogen followed by preparative electrophoresis. Thermolabile fragment. Complete proteolysis of a single fibrinogen molecule produces two D and one E fragments. Fragment D has been shown to increase endothelial monolayer permeability and to decrease polymorphonuclear leukocyte adhesion to endothelial cells. The D and E fragments have no common antigenic determinants; therefore, no cross-reactivity occurs.

Ostrzeżenie

Toxicity: Standard Handling (A)

Postać fizyczna

Lyophilized from 400 mM glycine, 150 mM NaCl.

Rekonstytucja

Following reconstitution, aliquot and freeze (-70°C). Stock solutions are stable for up to 4 h at 20°C or for up to 8 h at 4°C or for up to 3 months at -70°C.

Komentarz do analizy

single band by SDS-PAGE

Inne uwagi

Spraggon, G., et al. 1997. Nature 389, 455.
Stirk, C.M., et al. 1993. Atherosclerosis103, 159.
Vogel, P., et al. 1993. Eur. Surg. Res.25, 83.
Azpiazu, I., and Chapman, D. 1992. Biochim. Biophys. Acta1119, 268.
Thompson, W.D., et al. 1992. J. Pathol.168, 47.
Fisher, E.G., et al. 1991. Haemostasis21, 141.
Ge, M., et al. 1991. Am. J. Physiol.261, L283.

Informacje prawne

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

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Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 11 - Combustible Solids
• Klasa zagrożenia wodnego (WGK): WGK 1
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable