341482

Ferritin, Human Liver

Ferritin, Human Liver, CAS 9007-73-2, is a native, sterile-filtered ferritin that is suitable for use in immunoassays, as an immunogen, and in enzyme/radiolabeling.

• Synonim(y): Ferritin, Human Liver
• Numer CAS: 9007-73-2
• Numer MDL: MFCD00081593
• Kod UNSPSC: 12352202
• NACRES: NA.77

Właściwości

• pochodzenie biologiczne: human
• Poziom jakości: 100
• Próba: ≥95% (SDS-PAGE)
• Formularz: liquid
• producent / nazwa handlowa: Calbiochem^®
• warunki przechowywania: do not freeze
• metody: enzyme immunoassay: suitable
• zanieczyszczenia: Antibodies to HIV1, HIV2, Hepatitis B, Hepatitis C, tested negative (by certified tests)
• rozpuszczalność: water: soluble
• przydatność: suitable for immunoassay
• numer dostępu Protein ID: AAA35832.1
• numer dostępu UniProt: P02792; P02794
• Warunki transportu: wet ice
• temp. przechowywania: 2-8°C
• informacje o genach: human ... FTH1(2495) , FTL(2512)

Opis

Opis ogólny

Research area: Cell signaling

Ferritin is a major iron storage protein. It exists in a two functionally and genetically different subunits namely, the acidic, heavy or H-chain and the basic, light or L-chain. Native ferritin from human liver. Sterile-filtered.

Zastosowanie

Ferritin is suitable for use in immunofluorescence assay, immunoassays, as an immunogen, and in enzyme/radiolabeling.

Działania biochem./fizjol.

Ferritin is a crucial protein that has multiple functions in iron metabolism and immune regulation. It helps in maintaining the iron balance. H-ferritin is involved in various processes such as regulating immune function, hematopoiesis, hepatocyte apoptosis, and cell differentiation. Additionally, ferritin can act as a proinflammatory cytokine through protein kinase C-zeta (PKC-ζ) and nuclear factor kappa B (NFκB) signaling pathways in certain cells.(1) Ferritin serves as both an immune-suppressor and a signaling molecule, contributing to the regulation of lymphoid and myeloid cell proliferation.

Opakowanie

Please refer to vial label for lot-specific concentration.

Ostrzeżenie

Toxicity: Standard Handling (A)

Postać fizyczna

In 0.9% NaCl, 0.1% NaN₃, pH 7.0.

Inne uwagi

Addison, J.M., et al. 1983. FEBS Lett.164, 139.

Informacje prawne

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Oświadczenie o zrzeczeniu się odpowiedzialności

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.

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Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 12 - Non Combustible Liquids
• Klasa zagrożenia wodnego (WGK): WGK 2
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable