252926

N-Acetylneuraminic Acid, 2,3-Dehydro-2-deoxy-, Sodium Salt

Inhibitor of bacterial, viral, and mammalian neuraminidases. Ki = 4 µM for influenza virus neuraminidase. Believed to act by binding to the catalytic site of neuraminidase as a transition state analog.

• Synonim(y): N-Acetylneuraminic Acid, 2,3-Dehydro-2-deoxy-, Sodium Salt
• Wzór empiryczny (zapis Hilla): C₁₁H₁₆NNaO₈
• Masa cząsteczkowa: 313.24
• Kod UNSPSC: 12352201
• NACRES: NA.79

Właściwości

• Poziom jakości: 100
• Próba: ≥95% (TLC)
• Postać: solid
• producent / nazwa handlowa: Calbiochem^®
• warunki przechowywania: OK to freeze; desiccated (hygroscopic)
• kolor: off-white to pale yellow
• rozpuszczalność: water: 1 mM
• Warunki transportu: ambient
• temp. przechowywania: −20°C

Opis

Opis ogólny

A ganglioside neuraminidase inhibitor that is believed to act by binding to the catalytic site of neuraminidase. Reported to inhibit influenza virus neuraminidase (K_i = 4 µM). Also inhibits bacterial, viral, and mammalian neuraminidases.

Inhibitor of bacterial, viral, and mammalian neuraminidases. K_i = 4 µM for influenza virus neuraminidase. Believed to act by binding to the catalytic site of neuraminidase as a transition state analog.

Ostrzeżenie

Toxicity: Standard Handling (A)

Rekonstytucja

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.

Inne uwagi

Kopitz, J., et al. 1997. Eur. J. Cell. Biol.73, 1.
Holzer, C.T., et al. 1993. Glycoconj. J.10, 40.
Chong, A.K., et al. 1991. Biochem. Int.24, 165.

Informacje prawne

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

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Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 11 - Combustible Solids
• Klasa zagrożenia wodnego (WGK): WGK 1
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable