204910

Complement C9, Human

Complement C9, Human, CAS 80295-59-6, is a native, single-chain glycoprotein present in normal human serum at 60 µg/ml.

• Synonim(y): Complement C9, Human
• Numer CAS: 80295-59-6
• Numer MDL: MFCD00130849
• Kod UNSPSC: 12352202
• NACRES: NA.25

Właściwości

• Poziom jakości: 200
• Próba: ≥95% (SDS-PAGE)
• Postać: liquid
• aktywność właściwa: ≥150,000 C9H50 units/mg
• producent / nazwa handlowa: Calbiochem^®
• warunki przechowywania: OK to freeze; avoid repeated freeze/thaw cycles
• zanieczyszczenia: IgG, IgA, IgM, albumin, C3, C4, C5, C6, C7, or C8, trace
• Warunki transportu: wet ice
• temp. przechowywania: −70°C

Opis

Opis ogólny

Native, human C9 complement component. Single-chain glycoprotein present in normal human serum at 60 µg/ml. On activation of complement via either the classical or alternative pathway, formation of the C5b fragment initiates assembly of C5b-9 complement membrane attack complex (MAC) on target surfaces. Full lytic activity of MAC occurs only after binding of three to six C9 molecules to each C5b-8 complex.

Native, human C9 complement component. Single-chain glycoprotein present in normal human serum at 60 µg/ml. On activation of complement via either the classical or alternative pathway, formation of the C5b fragment initiates assembly of the C5b-9 complement membrane attack complex (MAC) on target surfaces. Full lytic activity of MAC occurs only after binding of three to six C9 molecules to each C5b-8 complex.

Opakowanie

Please refer to vial label for lot-specific concentration.

Ostrzeżenie

Toxicity: Standard Handling (A)

Postać fizyczna

In PBS, pH 7.2, filtered through a 0.22 µm pore size filter.

Uwaga dotycząca przygotowania

Prepared from serum that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.

Rekonstytucja

Following initial thaw, aliquot and freeze (-70°C).

Inne uwagi

Stanley, K.K., et al. 1985. EMBO J. 4, 375.
Biesecker, G. and Muller-Eberhard, H.J. 1980. J. Immunol. 124, 1291.

Informacje prawne

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

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Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 12 - Non Combustible Liquids
• Klasa zagrożenia wodnego (WGK): nwg
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable