2011

Bilirubin

solid, bile pigment, Calbiochem^®

• Synonim(y): Bilirubin
• Wzór empiryczny (zapis Hilla): C₃₃H₃₆N₄O₆
• Numer CAS: 635-65-4
• Masa cząsteczkowa: 584.66
• Numer MDL: MFCD00005499
• Kod UNSPSC: 12352200
• NACRES: NA.77

Właściwości

• product name: Bilirubin, Principal pigment of bile and one of the major end products of hemoglobin decomposition.
• Poziom jakości: 100
• Postać: solid
• producent / nazwa handlowa: Calbiochem^®
• warunki przechowywania: OK to freeze; protect from light
• kolor: red-brown
• rozpuszczalność: chloroform: 1 mg/mL; alkaline solution: soluble
• Warunki transportu: ambient
• temp. przechowywania: 10-30°C
• InChI: 1S/C33H36N4O6/c1-7-20-19(6)32(42)37-27(20)14-25-18(5)23(10-12-31(40)41)29(35-25)15-28-22(9-11-30(38)39)17(4)24(34-28)13-26-16(3)21(8-2)33(43)36-26/h7-8,13-14,34-35H,1-2,9-12,15H2,3-6H3,(H,36,43)(H,37,42)(H,38,39)(H,40,41)/b26-13-,27-14-
• Klucz InChI: BPYKTIZUTYGOLE-IFADSCNNSA-N

Opis

Opis ogólny

Bilirubin is an orange-yellow bile pigment and one of the major end products of hemoglobin decomposition. It contains conjugated double bonds and reactive hydrogen atoms. In adults, the upper limit of the normal range of bilirubin is >1mg/dL. Serum levels of bilirubin in healthy newborns are less than 15 mg/dl. This product corresponds to the unconjugated form.

Działania biochem./fizjol.

Bilirubin is reported to cross the blood-brain barrier and exert significant antioxidant effects in the brain. This pigment aids in coloration in the various forms of jaundice. Bilirubin levels act as biomarkers in liver and blood disorders. Unconjugated form of bilirubin at lower levels serves as a physiological antioxidant. However, increased concentration of bilirubin is toxic and leads to neonatal hyperbilirubinemia in neonates.

Rekonstytucja

Unstable in basic solutions; reconstitute just prior to use.

Inne uwagi

Extinction coefficient (454 nm, CHCl₃):59,100-62,300 M^-1cm^-1.
Cell permeable: no
Reversible: no
Product does not compete with ATP.
Primary Target

Informacje prawne

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

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Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 11 - Combustible Solids
• Klasa zagrożenia wodnego (WGK): WGK 2
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable