1.10110

2-[4-(2-Hydroxyethyl)-1-piperazinyl]-ethanesulfonic acid

Buffer substance HEPES EMPROVE^® EXPERT

• Synonim(y): HEPES, 4-(2-Hydroxyethyl)piperazine-1-ethanesulfonic acid, N-(2-Hydroxyethyl)piperazine-N′-(2-ethanesulfonic acid)
• Wzór empiryczny (zapis Hilla): C₈H₁₈N₂O₄S
• Numer CAS: 7365-45-9
• Masa cząsteczkowa: 238.30
• Beilstein: 883043
• Numer MDL: MFCD00006158
• Kod UNSPSC: 12161703
• Numer indeksu EC: 230-907-9

Właściwości

• Poziom jakości: 500
• linia produktu: EMPROVE^® EXPERT
• siła działania: >2000 mg/kg LD₅₀, oral (Rat)
• Właściwości: RNase and DNase free
• metody: API processing | cocrystal formation: suitable
• pH: 5.0-5.5 (20 °C, 100 g/L in H₂O)
• przydatny zakres pH: 6.8-8.2
• pKa (25°C): 7.5
• mp: 212.6 °C
• rozpuszczalność: 703.6 g/L
• gęstość: 1.44 g/cm³ at 20 °C
• gęstość nasypowa: 560 kg/m³
• temp. przechowywania: 2-25°C
• ciąg SMILES: OCCN1CCN(CC1)CCS(O)(=O)=O
• InChI: 1S/C8H18N2O4S/c11-7-5-9-1-3-10(4-2-9)6-8-15(12,13)14/h11H,1-8H2,(H,12,13,14)
• Klucz InChI: JKMHFZQWWAIEOD-UHFFFAOYSA-N

Opis

Opis ogólny

Our SAFC^® portfolio of high-quality products for biopharmaceutical processing withstands strict quality control procedures and is produced according to MQ-500 requirements as defined by the M-Clarity program.

M-Clarity Program

As part of our EMPROVE^® Program, our raw materials are offered with EMPROVE^® Dossiers which provide comprehensive, up-to-date documentation to help you navigate regulatory challenges, manage risks, and improve your manufacturing processes.
Buffer quality is vital for the success of biopharmaceutical processes, because buffers are indispensable in nearly every production step.

Our broad portfolio of buffer materials manufactured under appropriate controls is tailored to your needs. Ranging from non-GMP grades for low-risk application, to IPEC-PQG GMP for higher-risk applications, we have products covering all your manufacturing needs.

Informacje prawne

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

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Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 11 - Combustible Solids
• Klasa zagrożenia wodnego (WGK): WGK 1
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable