1.06346

Sodium dihydrogen phosphate monohydrate

for analysis EMSURE^® ACS,Reag. Ph Eur

• Synonim(y): Sodium phosphate monobasic monohydrate, Monosodium phosphate, Sodium dihydrogen phosphate monohydrate
• Wzór liniowy: NaH₂PO₄ · H₂O
• Numer CAS: 10049-21-5
• Masa cząsteczkowa: 137.99
• Numer MDL: MFCD00149208
• Kod UNSPSC: 12352302
• Numer indeksu EC: 231-449-2
• NACRES: NA.21

Właściwości

• klasa czystości: ACS reagent
• Poziom jakości: 300
• agency: reag. Ph. Eur.
• linia produktu: EMSURE^®
• Próba: 99.0-102.0% (alkalimetric)
• Postać: crystals
• siła działania: >2000 mg/kg LD₅₀, oral (Rat); >7940 mg/kg LD₅₀, skin (Rabbit)
• zanieczyszczenia: ≤0.01% Insoluble matter
• pH: 4.1-4.5 (25 °C, 50 g/L in H₂O)
• rozpuszczalność: 850 g/L
• gęstość: 2.04 g/cm³ at 20 °C
• gęstość nasypowa: 880 kg/m³
• ślady anionów: chloride (Cl^-): ≤0.0005%; sulfate (SO₄^2-): ≤0.003%
• ślady kationów: Ca: ≤0.005%; Fe: ≤0.0005%; K: ≤0.005%; N: ≤0.001%; heavy metals: ≤0.0005%
• absorpcja UV: λ: 280 nm A_max: ≤0.05
• temp. przechowywania: 2-30°C
• ciąg SMILES: [Na+].[H]O[H].OP(O)([O-])=O
• InChI: 1S/Na.H3O4P.H2O/c;1-5(2,3)4;/h;(H3,1,2,3,4);1H2/q+1;;/p-1
• Klucz InChI: BBMHARZCALWXSL-UHFFFAOYSA-M

Opis

Zastosowanie

• Development of a multiparticulate drug delivery system for in situ amorphisation.: This study explores the use of sodium dihydrogen phosphate monohydrate in developing a multiparticulate drug delivery system. The research highlights the compound′s role in achieving in situ amorphisation, enhancing drug solubility and bioavailability (Holm TP et al., 2022).


• Metabolomic characterization of rhubarb species by capillary electrophoresis and ultra-high-pressure liquid chromatography.: Sodium dihydrogen phosphate monohydrate is utilized in the buffer system for capillary electrophoresis and UHPLC, aiding in the metabolomic analysis of rhubarb species. This research underscores its importance in improving separation efficiency and resolution in analytical methods (Tseng YJ et al., 2013).

Powiązanie

Replaces: SX0709; SX0709-5; SX0710; SX0710-1; SX0710-3; SX0710-5; SX0710-20

Komentarz do analizy

Assay (alkalimetric): 99.0 - 102.0 %
Insoluble matter: ≤ 0.01 %
pH-value (5 %; water, 25 °C): 4.1 - 4.5
UV absorption (280 nm; 1 mol/l; 1 cm; water): ≤ 0.05
Chloride (Cl): ≤ 0.0005 %
Sulfate (SO₄): ≤ 0.003 %
Total nitrogen (N): ≤ 0.001 %
Heavy metals (ACS): ≤ 0.0005 %
Ca (Calcium): ≤ 0.005 %
Fe (Iron): ≤ 0.0005 %
K (Potassium): ≤ 0.005 %
Corresponds to ACS,Reag. Ph Eur

Informacje prawne

EMSURE is a registered trademark of Merck KGaA, Darmstadt, Germany

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Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 13 - Non Combustible Solids
• Klasa zagrożenia wodnego (WGK): WGK 3
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable