1.03893

Benzenesulfonic acid

EMPROVE^® EXPERT

• Synonim(y): Benzene sulphonic acid, Benzenesulphonic acid, Besylic acid, Phenylsulfonic acid, Phenylsulphonic acid
• Wzór liniowy: C₆H₅SO₃H
• Numer CAS: 98-11-3
• Masa cząsteczkowa: 158.18
• Beilstein: 742513
• Numer WE: 202-638-7
• Numer MDL: MFCD00011689
• Kod UNSPSC: 12352005

Właściwości

• pochodzenie biologiczne: synthetic
• Poziom jakości: 500
• linia produktu: EMPROVE^® EXPERT
• Formularz: crystalline
• metody: API processing | cocrystal formation: suitable; API processing | salt formation: suitable
• zanieczyszczenia: endotoxins, low
• Zastosowanie: liquid formulation; parenterals; pharmaceutical
• ciąg SMILES: OS(=O)(=O)c1ccccc1
• InChI: 1S/C6H6O3S/c7-10(8,9)6-4-2-1-3-5-6/h1-5H,(H,7,8,9)
• Klucz InChI: SRSXLGNVWSONIS-UHFFFAOYSA-N

Opis

Opis ogólny

For protein-based therapeutics, such as monoclonal antibodies (mAbs) or plasma derived proteins, often highly concentrated protein formulations are required to meet intended dosing regimens. However, this usually comes with elevated viscosities and presents a challenge in the manufacturing process and final formulation. Our Viscosity Reduction Excipient Platform reduces the viscosity and helps overcome challenges associated with highly concentrated protein solutions.
As part of our Emprove^® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation.
Our SAFC^® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Zastosowanie

The Viscosity Reduction Platform is based on the combination of two new excipients, one amino acid component with one anionic component, that together can better reduce protein viscosity beyond levels achieved with single excipients. Also, combining the two components enables a balance of viscosity reduction and protein stabilization. Benzenesulfonic Acid Emprove^® Expert is part of this new proprietary technology platform.

Opakowanie

1038930500 / 500g / Glass bottle
1038931000 / 1kg / Glass bottle

Informacje prawne

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

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Informacja o środkach bezpieczeństwa

• Piktogramy: GHS05,GHS07
• Hasło ostrzegawcze: Danger
• Zwroty wskazujące rodzaj zagrożenia: H302,H314
• Zwroty wskazujące środki ostrożności: P260 - P270 - P280 - P301 + P312 - P303 + P361 + P353 - P305 + P351 + P338
• Klasyfikacja zagrożeń: Acute Tox. 4 Oral - Eye Dam. 1 - Skin Corr. 1B
• Kod klasy składowania: 8A - Combustible corrosive hazardous materials
• Klasa zagrożenia wodnego (WGK): WGK 1