07-436-AF488

Anti-monomethyl Histone H3 (Lys4) Antibody, Alexa Fluor^™ 488 Conjugate

0.5 mg/mL, from rabbit

• Synonim(y): Histone H3.1t, H3/t, H3t, H3/g
• Kod UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Właściwości

• pochodzenie biologiczne: rabbit
• Poziom jakości: 100
• białko sprzężone: ALEXA FLUOR^™ 488
• forma przeciwciała: purified antibody
• rodzaj przeciwciała: primary antibodies
• klon: polyclonal
• reaktywność gatunkowa: human
• reaktywność gatunkowa (przewidywana na podstawie homologii): vertebrates (based on 100% sequence homology)
• stężenie: 0.5 mg/mL
• metody: immunocytochemistry: suitable
• numer dostępu NCBI: NM_003493
• numer dostępu UniProt: Q16695
• Warunki transportu: wet ice
• docelowa modyfikacja potranslacyjna: monomethylation (Lys4)
• informacje o genach: human ... H3C1(8350)

Opis

Opis ogólny

Histone H3 is one of the five main histone proteins involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and a long N-terminal tail, H3 is involved with the structure of the nucleosomes of the ′beads on a string′ structure. Histone proteins are highly post-translationally modified, and Histone H3 is the most extensively modified of the five histones. Histone H3 sequence variants and variable modification states are thought to play a role in the dynamic and long term regulation of genes. Di- and tri-methylation of histone H3 are gene silencing marks, while removal of these marks by the demethylase genes Jmjd1a and Jmjd2c leads to gene activation. This product is a conjugated version of Cat. No. 07-436.

Immunogen

Linear peptide corresponding to Histone H3 monomethylated at Lys4.

Zastosowanie

This Anti-monomethyl Histone H3 (Lys4) Antibody, Alexa Fluor^™ 488 Conjugate is validated for use in ICC for the detection of monomethyl Histone H3 (Lys4).

Jakość

Evaluated by Immunocytochemisty Analysis in HeLa cells.

Immunocytochemistry Analysis: A 1:100 dilution of this antibody detected monomethyl Histone H3 (Lys4) in HeLa cells.

Alexa Fluor^™ is a registered trademark of Life Technologies.

Opis wartości docelowych

~17 kDa observed (Refer to Cat. No. 07-436)

Postać fizyczna

Purified rabbit Alexa Fluor^™ 488 conjugated antibody in buffer containing PBS with 15 mg/ml BSA and 0.1% Sodium Azide.

Informacje prawne

ALEXA FLUOR is a trademark of Life Technologies

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Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 12 - Non Combustible Liquids
• Klasa zagrożenia wodnego (WGK): WGK 2
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable