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803588
BM(PEG)2 (1,8-bismaleimido-diethyleneglycol)
Synonim(y):
1,2-Bis(2-maleimidoethoxy)ethane, 1,8-Bis(maleimido)-3,6-dioxaoctane
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About This Item
Wzór empiryczny (zapis Hilla):
C14H16N2O6
Numer CAS:
Masa cząsteczkowa:
308.29
Numer MDL:
Kod UNSPSC:
12352200
Identyfikator substancji w PubChem:
NACRES:
NA.22
Polecane produkty
Próba
≥90%
Postać
powder
masa cząsteczkowa
308.29
przydatność reakcji
reagent type: cross-linking reagent
warunki przechowywania
desiccated
rozpuszczalność
water: soluble
Warunki transportu
ambient
temp. przechowywania
2-8°C
ciąg SMILES
O=C(C=CC1=O)N1CCOCCOCCN2C(C=CC2=O)=O
InChI
1S/C14H16N2O6/c17-11-1-2-12(18)15(11)5-7-21-9-10-22-8-6-16-13(19)3-4-14(16)20/h1-4H,5-10H2
Klucz InChI
FERLGYOHRKHQJP-UHFFFAOYSA-N
Opis ogólny
BM(PEG)2 and BM(PEG)3 are homobifunctional, maleimide crosslinkers for conjugation between sulfhydryl groups (-SH). Such bismaleimide crosslinkers are commonly used to explore and characterize protein structure (i.e. oligomerization) or protein interactions. Because BM(PEG)2 and BM(PEG)3 have the same reactivity but differ in length, the relative success of these and similar reagents in forming crosslinks between sites in a protein oligomer or interaction can assist in determining intra- and intermolecular distances.
Cechy i korzyści
- Reactive groups: maleimide (both ends)
- Reactive towards: sulfhydryl groups
- Long, pegylated, sulfhydryl-to-sulfhydryl crosslinkers, composed of maleimide groups and 2-unit polyethylene glycol spacer arm
- PEG spacers provide unique advantages, including enhanced solubility, increased stability, reduced tendency toward aggregation and reduced immunogenicity
- Pure compounds with defined structure and molecular weight, ensuring reproducible protein-modification effects
- Ideal for small molecule or peptide conjugations
Przestroga
This product is sensitive to moisture. The vial is packaged in a resealable bag with a desiccant to reduce exposure to moisture. After cold storage, equilibrate the vial to room temperature before opening to reduce condensation inside the vial. Make fresh solutions. Storage of stock solutions is not recommended. After use, return the vial to the resealable bag. Close the bag and store the product at the recommended temperature.
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Hasło ostrzegawcze
Warning
Zwroty wskazujące rodzaj zagrożenia
Zwroty wskazujące środki ostrożności
Klasyfikacja zagrożeń
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Organy docelowe
Respiratory system
Kod klasy składowania
11 - Combustible Solids
Klasa zagrożenia wodnego (WGK)
WGK 3
Temperatura zapłonu (°F)
Not applicable
Temperatura zapłonu (°C)
Not applicable
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