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Merck

735094

Sigma-Aldrich

Bis(2-methacryloyl)oxyethyl disulfide

contains ≤6000 ppm hydroquinone as stabilizer

Synonim(y):

DSDMA, Disulfide-based dimethacrylate

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About This Item

Wzór empiryczny (zapis Hilla):
C12H18O4S2
Numer CAS:
Masa cząsteczkowa:
290.40
Numer MDL:
Kod UNSPSC:
12162002
Identyfikator substancji w PubChem:
NACRES:
NA.23

Formularz

liquid

zawiera

≤6000 ppm hydroquinone as stabilizer

współczynnik refrakcji

n20/D 1.517

gęstość

1.141 g/mL at 25 °C

temp. przechowywania

2-8°C

ciąg SMILES

CC(=C)C(=O)OCCSSCCOC(=O)C(C)=C

InChI

1S/C12H18O4S2/c1-9(2)11(13)15-5-7-17-18-8-6-16-12(14)10(3)4/h1,3,5-8H2,2,4H3

Klucz InChI

CGDNFXSLPGLMHK-UHFFFAOYSA-N

Opis ogólny

Bis(2-methacryloyl)oxyethyl disulfide (DSDMA) belongs to the class of monomers known as disulfide-based dimethacrylates. It is widely employed as a crosslinker in the synthesis of various polymers with specific properties such as redox sensitivity and self-healing properties. DSDMA contains a disulfide bond, which can be cleaved under specific conditions, making it useful for drug delivery systems. It also undergoes thiol-disulfide exchange reactions, allowing it to react with thiols in polymers and form covalent crosslinks. This property enables the formation of networks and gels in polymer systems. Additionally, DSDMA is employed in the development of biomedical materials, such as tissue engineering scaffolds. Its ability to form stable crosslinks in biological environments makes it suitable for these applications.

Zastosowanie

Bis(2-methacryloyl)oxyethyl disulfide (DSDMA) can be used in the following applications:
  • Used as a crosslinker in the synthesis of reduction-responsive molecularly imprinted polymer (MIPs) nanogels for drug delivery applications. This reduction-responsive property allows for control over drug delivery and modulation of the release properties of the MIPs.
  • Used as a crosslinker in the synthesis of self-healing polymer nanocomposites via dynamic disulfide exchange reaction and crosslinking properties. These self-healing polymer nanocomposites can be used in coatings, electronics, and packaging applications.
  • Used as a redox-responsive cross-linker in the synthesis of zwitterionic hydrogels for effective drug delivery. DSDMA provides structural stability, redox-responsiveness, and self-healing properties, which are essential for effective drug delivery.
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Piktogramy

Environment

Zwroty wskazujące rodzaj zagrożenia

Zwroty wskazujące środki ostrożności

Klasyfikacja zagrożeń

Aquatic Chronic 2

Kod klasy składowania

10 - Combustible liquids

Klasa zagrożenia wodnego (WGK)

WGK 3

Temperatura zapłonu (°F)

Not applicable

Temperatura zapłonu (°C)

Not applicable


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Odwiedź Bibliotekę dokumentów

Wenwen Li; Krzysztof Matyjaszewski; Krystyna Albrecht; Martin Moller
Macromolecules, 42, 8228-8228 (2009)
Kunihiko Kobayashi et al.
ACS applied materials & interfaces, 11(1), 151-159 (2018-12-12)
Soft-robotic devices such as polymeric microgrippers offer the possibility for pick and place of fragile biological cargo in hard-to-reach conduits with potential applications in drug delivery, minimally invasive surgery, and biomedical engineering. Previously, millimeter-sized self-folding thermomagnetically responsive soft grippers have
David S Spencer et al.
Journal of polymer science. Part A, Polymer chemistry, 56(14), 1536-1544 (2019-03-25)
Crosslinked cationic nanoscale networks with hydrophobic cores are an environmentally robust alternative to self-assembled polymeric drug delivery carriers with respect to therapeutic encapsulation and stability to dilution. However, the ability to tune the degree of PEG incorporated into nanogels during

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