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202487

Sigma-Aldrich

Poly(ethylene glycol) methyl ether

average MN 550, methoxy, hydroxyl

Synonim(y):

Glikol polietylenowy

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About This Item

Wzór liniowy:
CH3(OCH2CH2)nOH
Numer CAS:
9004-74-4
Numer MDL:
MFCD00084416
Kod UNSPSC:
12162002
Identyfikator substancji w PubChem:
24852066
NACRES:
NA.23

Nazwa produktu

Poly(ethylene glycol) methyl ether, average Mn 550

gęstość pary

>1 (vs air)

ciśnienie pary

0.05 mmHg ( 20 °C)

Formularz

semisolid

masa cząsteczkowa

average Mn 550

współczynnik refrakcji

n20/D 1.455

lepkość

7.5 cSt(210 °F)(lit.)

temp. przejścia

Tm 20 °C

gęstość

1.089 g/mL at 25 °C

Ω-koniec

hydroxyl

α-koniec

methoxy

ciąg SMILES

O(CCO)C

InChI

1S/C3H8O2/c1-5-3-2-4/h4H,2-3H2,1H3

Klucz InChI

XNWFRZJHXBZDAG-UHFFFAOYSA-N

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Zastosowanie

Poly(ethylene glycol) methyl ether can be used as a pore-forming agent to prepare polysulfone membranes with enhanced hydrophilicity.

Poly(ethylene glycol) methyl ether-grafted polyamidoamine (PAMAM) dendrimers can be used as drug carrier systems for anticancer drugs.
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Kod klasy składowania

10 - Combustible liquids

Klasa zagrożenia wodnego (WGK)

WGK 1

Temperatura zapłonu (°F)

359.6 °F - closed cup

Temperatura zapłonu (°C)

182 °C - closed cup

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Certyfikaty analizy (CoA)

Lot/Batch Number
MKCN8241
MKCL2387
MKCH8837
MKCF0413
MKCB0160V

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Polyethylene glycol dimethyl ether 500 (stabilised) for synthesis

Sigma-Aldrich

8.14171

Polyethylene glycol dimethyl ether 500

Smita K Pawar et al.
International journal of pharmaceutics, 436(1-2), 183-193 (2012-06-23)
Efficacy of anticancer drug is limited by the severe adverse effects induced by drug; therefore the crux is in designing delivery systems targeted only to cancer cells. Toward this objectives, we propose, synthesis of poly(ethylene glycol) (PEG)-doxorubicin (DOX) prodrug conjugates
Mark G P Saifer et al.
Molecular immunology, 57(2), 236-246 (2013-11-10)
The use of methoxypoly(ethylene glycol) (mPEG) in PEG conjugates of proteins and non-protein therapeutic agents has led to the recognition that the polymer components of such conjugates can induce anti-PEG antibodies (anti-PEGs) that may accelerate the clearance and reduce the
Jiani Zheng et al.
Langmuir : the ACS journal of surfaces and colloids, 28(37), 13261-13273 (2012-08-28)
Alginate/chitosan/alginate (ACA) hydrogel microcapsules were modified with methoxy poly(ethylene glycol) (MPEG) to improve protein repellency and biocompatibility. Increased MPEG surface graft density (n(S)) on hydrogel microcapsules was achieved by controlling the grafting parameters including the buffer layer substrate, membrane thickness
Mulu Z Tesfay et al.
Journal of virology, 87(7), 3752-3759 (2013-01-18)
We are developing oncolytic vesicular stomatitis viruses (VSVs) for systemic treatment of multiple myeloma, an incurable malignancy of antibody-secreting plasma cells that are specifically localized in the bone marrow. One of the presumed advantages for using VSV as an oncolytic
Seung-Young Lee et al.
Biomaterials, 34(2), 552-561 (2012-10-20)
Although targeted delivery mediated by ligand modified or tumor microenvironment sensitive nanocarriers has been extensively pursued for cancer chemotherapy, the efficiency is still limited by premature drug release after systemic administration. Herein we report a highly blood-stable, tumor-adaptable drug carrier
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