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TP53

tumor protein p53

Synonimy:
BCC7, LFS1, P53, TRP53
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(7157) Summary: This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons (PMIDs: 12032546, 20937277). [provided by RefSeq, Feb 2013]
  • Rat(24842) tumor protein p53
  • Zebrafish(30590) tumor protein p53
  • Horse(100062044) tumor protein p53
  • domestic cat(493847) tumor protein p53
  • dog(403869) tumor protein p53
  • chicken(396200) tumor protein p53
  • cow(281542) tumor protein p53
  • sheep(443421) tumor protein p53
  • domestic guinea pig(100379269) tumor protein p53
  • Domestic Rabbit(100009292) tumor protein p53
  • naked mole-rat(101701769) tumor protein p53

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ELISA

Numer produktu
Opis
Gatunek
Rat Tp53 / Cellular Tumor Antigen p53 ELISA Kit, ,
Gatunek
rat
Human p53 ELISA Kit, for serum, plasma, cell culture supernatant and urine,
Gatunek
human

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-p53 antibody, Mouse monoclonal, clone BP53-12, ascites fluid,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
immunocytochemistry

immunohistochemistry

immunoprecipitation (IP)

microarray

western blot
Anti-TP53 (ab3) antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
bovine, human, pig, rabbit, sheep
Zastosowanie
ChIP
immunohistochemistry

western blot
Monoclonal Anti-p53−Biotin antibody produced in mouse, ~1 mg/mL, clone DO-1, ascites fluid, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
flow cytometry
immunocytochemistry

immunohistochemistry

immunoprecipitation (IP)

western blot
Anti-Acetyl (Lys 319) p53 Antibody, C-Terminal antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
ELISA
immunofluorescence

western blot
Anti-p53 (Acetyl-Lys379), C-Terminal antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
ELISA
immunofluorescence

immunohistochemistry

Cell Lines

Numer produktu
Opis
Gatunek
MCF10A CELLS TP53 (-/-), ,
Gatunek
human
SW48 Cells TP53 -/-, ,
Gatunek
human
DLD1 Cells TP53 -/-, ,
Gatunek
human

Small Molecule - Inhibitor

Numer produktu
Opis
Gatunek
CP-31398 dihydrochloride hydrate, ≥98% (HPLC),
Gatunek
mouse, rat, human

Proteins

Numer produktu
Opis
Gatunek
p53 human, recombinant, expressed in baculovirus infected Sf21 cells,
Gatunek
human
p53 human, recombinant, expressed in E. coli, buffered aqueous glycerol solution,
Gatunek
human
p53 (1-342) C-terminal deletion human, recombinant, expressed in insect cells, ≥80% (SDS-PAGE),
Gatunek
human
p53 (1-81), mutant, GST tagged human, recombinant, expressed in E. coli, ≥80% (SDS-PAGE),
Gatunek
human
p53 (1-363) C-terminal deletion human, recombinant, expressed in insect cells, ≥80% (SDS-PAGE),
Gatunek
human

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting human TP53,
Gatunek
human